Alexandra L. Zakharenko

Author

Siberian Branch of the Russian Academy of Sciences

Also Known As

Alexandra L. Zakharenko, Alexandra Leonidovna Zakharenko, Alexandra Zakharenko, Zakharenko, Alexandra L.

Publications

1.1K

Citations

H-Index

Concepts

All Affiliations

Siberian Branch of the Russian Academy of Sciences Institute of Chemical Biology and Fundamental Medicine Novosibirsk Institute of Organic Chemistry Novosibirsk State University University of Auckland

About

Alexandra L. Zakharenko is an author at Siberian Branch of the Russian Academy of Sciences specializing in natural sciences, drug discovery, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	10	11	386
2	Biochemistry	9	9	326
3	Medicine	8	8	336
4	Biomolecular Engineering	3	3	63
5	Engineering	1	1	14

Alexandra L. Zakharenko

Publications

966

Citations

H-Index

Page 1

	Year	Citations
Synthesis and biological evaluation of novel tyrosyl-DNA phosphodiesterase 1 inhibitors with a benzopentathiepine moiety Alexandra L. Zakharenko, O. A. Koval, Olga D. Zakharova, Bioorganic & Medicinal Chemistry Medicinal ChemistryBiochemistryNatural SciencesMedicineBioconjugation	2015	86
Tyrosyl-DNA Phosphodiesterase 1 Inhibitors: Usnic Acid Enamines Enhance the Cytotoxic Effect of Camptothecin Alexandra L. Zakharenko, Olga A. Luzina, O. A. Koval, Journal of Natural Products	2016	78
New inhibitors of tyrosyl-DNA phosphodiesterase I (Tdp 1) combining 7-hydroxycoumarin and monoterpenoid moieties Alexandra L. Zakharenko, Tatyana Odarchenko, Homayon J. Arabshahi, Bioorganic & Medicinal Chemistry Medicinal ChemistryBioorganic ChemistryTyrosyl-dna PhosphodiesteraseBiochemistryNatural Sciences	2016	59
Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy Alexandra L. Zakharenko, Arina A. Chepanova, Ekaterina S. Ilina, International Journal of Molecular Sciences	2019	51
A synthesis, in silico, in vitro and in vivo study of thieno[2,3-b]pyridine anticancer analogues Homayon J. Arabshahi, Michelle van Rensburg, Lisa I. Pilkington, MedChemComm Vivo StudyMedicinal ChemistryNatural SciencesMedicineMolecular Biology	2015	50
New Hydrazinothiazole Derivatives of Usnic Acid as Potent Tdp1 Inhibitors Aleksandr S. Filimonov, Arina A. Chepanova, Olga A. Luzina, Molecules	2019	47
Aminoadamantanes containing monoterpene-derived fragments as potent tyrosyl-DNA phosphodiesterase 1 inhibitors Konstantin Ponomarev, Alexandra L. Zakharenko, Olga D. Zakharova, Bioorganic Chemistry Medicinal ChemistryPharmaceutical ScienceMonoterpene-derived FragmentsBiochemistryMedicine	2017	39
Synthesis and evaluation of aryliden- and hetarylidenfuranone derivatives of usnic acid as highly potent Tdp1 inhibitors Olga D. Zakharova, Olga A. Luzina, Alexandra L. Zakharenko, Bioorganic & Medicinal Chemistry Medicinal ChemistryDerivative (Chemistry)BiochemistryMedicineNatural Sciences	2018	33
A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2H-chromen-4-ol Scaffold Alexandra L. Zakharenko, Arina A. Chepanova, Jinal Patel, Molecules	2018	33
Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1 Nadezhda S. Dyrkheeva, Alexandra L. Zakharenko, A.Yu. Sidorenko, Molecules	2020	33

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