R. F. SCHINAZI

The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance

Naoya Kato, Yasushi Shiratori, Jun Kato et al. · Journal of Clinical Investigation · 2001 · 272 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Line probe assay for rapid detection of drug-selected mutations in the human immunodeficiency virus type 1 reverse transcriptase gene

Lieven Stuyver, Ann Wyseur, Annelies Rombout et al. · Antimicrobial Agents and Chemotherapy · 1997 · 236 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

Anthraquinones as a new class of antiviral agents against human immunodeficiency virus

R. F. SCHINAZI, Chung K. Chu, Janga Ramesh Babu et al. · Antiviral Research · 1990 · 178 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells

Chung K. Chu, R. F. SCHINAZI, Moon K. Ahn et al. · Journal of Medicinal Chemistry · 1989 · 117 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Catabolism of 3'-azido-3'-deoxythymidine in hepatocytes and liver microsomes, with evidence of formation of 3'-amino-3'-deoxythymidine, a highly toxic catabolite for human bone marrow cells.

E M Cretton, Mengyu Xie, Ruth Bevan et al. · Molecular Pharmacology · 1991 · 106 citations

Life Sciences, Biochemistry, Cellular Biochemistry +7