Yukari Hirata

Discovery and in vitro and in vivo profiles of 4-fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as novel class of an orally active metabotropic glutamate receptor 1 (mGluR1) antagonist

Atsushi Satoh, Yasushi Nagatomi, Yukari Hirata et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 102 citations · Full text

Vivo Profiles, Biochemistry, Functional Selectivity +8

Discovery and biological profile of isoindolinone derivatives as novel metabotropic glutamate receptor 1 antagonists: A potential treatment for psychotic disorders

Satoru Ito, Yukari Hirata, Yasushi Nagatomi et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 62 citations · Full text

Psychoactive Drug, Psychiatry, Functional Selectivity +13

Discovery and biological profile of 4-(1-aryltriazol-4-yl)-tetrahydropyridines as an orally active new class of metabotropic glutamate receptor 1 antagonist

Satoru Ito, Atsushi Satoh, Yasushi Nagatomi et al. · Bioorganic & Medicinal Chemistry · 2008 · 53 citations · Full text

Functional Selectivity, Medicine, Biological Profile +7

Sensitive analysis of aconitine, hypaconitine, mesaconitine and jesaconitine in human body fluids and <i>Aconitum</i> tubers by LC/ESI‐TOF‐MS

Rina Kaneko, Satoshi Hattori, Shiho Furuta et al. · Journal of Mass Spectrometry · 2006 · 43 citations

Sensitive Analysis, Pharmacological Study, Bioanalysis +17

Brain changes in rats induced by prenatal injection of methylazoxymethanol

Masao Tamaru, Yukari Hirata, Michiko Nagayoshi et al. · Teratology · 1988 · 35 citations