Cardiac-specific overexpression of angiotensin II AT2 receptor causes attenuated response to AT1 receptor-mediated pressor and chronotropic effects.

Hiroya Masaki, Tatsuya Kurihara, Akira Yamaki, +12

Journal of Clinical Investigation

Cardiac MuscleHypertensionCardiovascular PharmacologyAng IiAt1 Receptor-mediated Pressor +17

Comparison of Sedative Effects Induced by Medetomidine, Medetomidine-Midazolam and Medetomidine-Butorphanol in Dogs.

Kei Hayashi, Ryohei Nishimura, Akira Yamaki, +4

Journal of Veterinary Medical Science

Ghrelin improves body weight loss and skeletal muscle catabolism associated with angiotensin II-induced cachexia in mice

Masako Sugiyama, Akira Yamaki, Mayumi Furuya, +4

Regulatory Peptides

Animal PhysiologyMetabolic SyndromeEnergy HomeostasisBody Weight LossAppetite Control +10

Suppression of Cytokines and Nitric Oxide Production, and Protection Against Lethal Endotoxemia and Viral Myocarditis by a New NF-κB Inhibitor

Akira Matsumori, Youichi Nunokawa, Akira Yamaki, +7

European Journal of Heart Failure

Gene Expression of Cardiac Mast Cell Chymase and Tryptase in a Murine Model of Heart Failure Caused by Viral Myocarditis

Katsura Kitaura‐Inenaga, Masatake Hara, Kazuhiro Higuchi, +7

Circulation Journal

The role of C-terminal part of ghrelin in pharmacokinetic profile and biological activity in rats

Naomi Morozumi, Takeshi Hanada, Hiromi Habara, +7

Peptides

Biological ActivityBiochemistryPharmacokinetic ProfileMedicineNatural Sciences +8

Cardiopulmonary Effects of Medetomidine, Medetomidine-Midazolam and Medetomidine-Midazolam-Atipamezole in Dogs.

Ryohei Nishimura, Akira Yamaki, S Matsunaga, +2

Journal of Veterinary Medical Science

HypertensionHeart RateCardiac AnaesthesiaCardiovascular DiseaseCardiopulmonary Effects +10

Studies on Antihypertensive Agents with Antithrombotic Activity. 2. Syntheses and Pharmacological Evaluation of Pyrrolo[2,3-c]azepine Derivatives.

Akira Mizuno, Mikiko Miya, Makoto Shibata, +6

Chemical and Pharmaceutical Bulletin

Hypertension-Receptor AntagonistsCardiovascular PharmacologyPharmacotherapyPharmaceutical Chemistry +14

Discovery and dimeric approach of novel Natriuretic Peptide Receptor A (NPR-A) agonists

Takehiko Iwaki, Yoshiaki Oyama, Toshiyuki Tomoo, +5

Bioorganic & Medicinal Chemistry

BiochemistryMedicinePeptide LibraryReceptor (Biochemistry)Neuropeptide Receptor +4

Discovery and in vivo effects of novel human natriuretic peptide receptor A (NPR-A) agonists with improved activity for rat NPR-A

Takehiko Iwaki, Taisaku Tanaka, Kazuo Miyazaki, +7

Bioorganic & Medicinal Chemistry

Molecular PhysiologySignal TransductionBiochemistryImproved ActivityMedicine +10