Aberrant Epidermal Growth Factor Receptor Signaling and Enhanced Sensitivity to EGFR Inhibitors in Lung Cancer

Joseph M. Amann, Shailaja Kalyankrishna, Pierre P. Massion, +14

Cancer Research

MedicineCancer GrowthPathologyEgfr InhibitorsNsclc Cells +11

Deletion of Histone Deacetylase 3 Reveals Critical Roles in S Phase Progression and DNA Damage Control

Srividya Bhaskara, Brenda Chyla, Joseph M. Amann, +4

Molecular Cell

Histone ModificationsChromatinGenome InstabilityHistone Deacetylase 3Dna Damage Control +9

ETO, a Target of t(8;21) in Acute Leukemia, Makes Distinct Contacts with Multiple Histone Deacetylases and Binds mSin3A through Its Oligomerization Domain

Joseph M. Amann, John Nip, David K. Strom, +6

Molecular and Cellular Biology

Liver‐specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks

Sarah K. Knutson, Brenda Chyla, Joseph M. Amann, +3

The EMBO Journal

Both TEL and AML-1 Contribute Repression Domains to the t(12;21) Fusion Protein

Randy Fenrick, Joseph M. Amann, Bart Lutterbach, +4

Molecular and Cellular Biology

Molecular RegulationMolecular BiologyTranscriptional RegulationSignaling PathwayCell Regulation +14

EGFR Blockade Enriches for Lung Cancer Stem–like Cells through Notch3-Dependent Signaling

Rajeswara Rao Arasada, Joseph M. Amann, Mohammad Aminur Rahman, +2

Cancer Research

Notch3-dependent SignalingKinase InhibitorsCancer BiologyTumor BiologyCancer Cell Biology +17

Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma

Jill M. Lahti, Marcus Valentine, Jialing Xiang, +6

Nature Genetics

ChromatinDevelopmental BiologyPitslre ProteinCell RegulationGenetic Disorder +7

Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma

Marcin Imieliński, Heidi Greulich, Bethany Kaplan, +7

Journal of Clinical Investigation

OncologySomatic VariantOncogenic AgentOral SorafenibMedicine +12

TEL, a Putative Tumor Suppressor, Modulates Cell Growth and Cell Morphology of Ras-Transformed Cells While Repressing the Transcription of <i>stromelysin-1</i>

Randy Fenrick, Lilin Wang, John Nip, +8

Molecular and Cellular Biology

LKB1 Loss Induces Characteristic Patterns of Gene Expression in Human Tumors Associated with NRF2 Activation and Attenuation of PI3K-AKT

Jacob M. Kaufman, Joseph M. Amann, Kyungho Park, +4

Journal of Thoracic Oncology