Molecular Design, Synthesis, and Hypoglycemic Activity of a Series of Thiazolidine-2,4-diones

Minoru Oguchi, Kunio Wada, Hidehito Honma, +8

Journal of Medicinal Chemistry

Imidazopyridine Thiazolidine-2,4-dionesEngineeringBiochemistryMedicineDrug Discovery +12

JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results

Yoshifumi Uno, Hajime Kojima, Takashi Omori, +25

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

OncologyMedicineGenotoxic CarcinogensPathologyToxicology Testing +5

Anti-tumour activity of CS-7017, a selective peroxisome proliferator-activated receptor gamma agonist of thiazolidinedione class, in human tumour xenografts and a syngeneic tumour implant model

Naomi Shimazaki, Noriko Togashi, Masaharu Hanai, +5

European Journal of Cancer

Human Tumour XenograftsThiazolidinedione ClassMedicineAnti-tumour ActivityRadiopharmaceutical Therapy +8

The PIGRET assay, a method for measuring Pig-a gene mutation in reticulocytes, is reliable as a short-term in vivo genotoxicity test: Summary of the MMS/JEMS-collaborative study across 16 laboratories using 24 chemicals

Takafumi Kimoto, Katsuyoshi Horibata, Daishiro Miura, +31

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Effects of seven chemicals on DNA damage in the rat urinary bladder: A comet assay study

Kunio Wada, Toshinori Yoshida, Naofumi Takahashi, +1

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Endocrine DisruptorsDna DamageBiochemistryMedicineNatural Sciences +8

Physical interaction between SLX4 (FANCP) and XPF (FANCQ) proteins and biological consequences of interaction-defective missense mutations

Keiji Hashimoto, Kunio Wada, Kyomu Matsumoto, +1

DNA repair

Interaction-defective Missense MutationsGeneticsMolecular BiologyPhysical InteractionBiological Consequences +4

Studies of as-Triazine Derivatives. XV. Intramolecular Reverse-Election Demand Diels-Alder Reaction of 1,2,4-Triazine Derivatives

Hiroshi Yamanaka, M. SAGI, Kunio Wada, +1

Heterocycles

5,6-Diphenyl-1,2,4-triazine-3-carboxylic Acid EstersPyridine DerivativesDerivative (Chemistry)DerivativesEngineering +9

Immunotoxicity in mice induced by short-term exposure to methoxychlor, parathion, or piperonyl butoxide

Tomoki Fukuyama, Tadashi Kosaka, Kôichi Hayashi, +6

Journal of Immunotoxicology

ImmunotoxicologyImmunologyEnvironmental AgentsShort-term ExposureToxicological Mechanism +17

Assessment of the in vivo genotoxicity of cadmium chloride, chloroform, and d,l-menthol as coded test chemicals using the alkaline comet assay

Kunio Wada, Tomoki Fukuyama, Nobuaki Nakashima, +1

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

EngineeringEnvironmental EngineeringMedicineCadmium ChlorideToxicology Testing +10

Measuring reproducibility of dose response data for the Pig-a assay using covariate benchmark dose analysis

George E. Johnson, Mika Yamamoto, Yuta Suzuki, +11

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Animal ScienceLaboratory Animal StudyPharmacologyVeterinary ScienceDose Response Data +9