Metformin for chemoprevention of metachronous colorectal adenoma or polyps in post-polypectomy patients without diabetes: a multicentre double-blind, placebo-controlled, randomised phase 3 trial

Takuma Higurashi, Kunihiro Hosono, Hirokazu Takahashi, +16

The Lancet Oncology

Post-polypectomy PatientsSurgical OncologyDiabetes ManagementColorectal SurgeryRandomised Phase 3 +8

Oral administration of lactoferrin reduces colitis in rats via modulation of the immune system and correction of cytokine imbalance

Jun-Ichi Togawa, Hajime Nagase, Katsuaki Tanaka, +5

Journal of Gastroenterology and Hepatology

Lactoferrin reduces colitis in rats via modulation of the immune system and correction of cytokine imbalance

Jun-Ichi Togawa, Hajime Nagase, Katsuaki Tanaka, +7

American Journal of Physiology-Gastrointestinal and Liver Physiology

InflammationBovine LactoferrinTrinitrobenzenesulfonic AcidAnti-inflammatoryAutoimmune Disease +13

Risk factors for small-bowel mucosal breaks in chronic low-dose aspirin users: data from a prospective multicenter capsule endoscopy registry

Hiroki Endo, Eiji Sakai, Leo Taniguchi, +15

Gastrointestinal Endoscopy

Gastrointestinal PharmacologyPatient SafetyGastroenterologySmall-bowel Mucosal BreaksOutcomes Research +4

Clinical characteristics of Japanese reflux esophagitis patients as determined by Los Angeles classification

Masahiko Inamori, Jun-Ichi Togawa, Hajime Nagase, +12

Journal of Gastroenterology and Hepatology

Metformin efficacy and safety for colorectal polyps: a double-blind randomized controlled trial

Takuma Higurashi, Hirokazu Takahashi, Hiroki Endo, +16

BMC Cancer

Regulation of feeding behavior, gastric emptying, and sympathetic nerve activity to interscapular brown adipose tissue by galanin and enterostatin: the involvement of vagal-central nervous system interactions

Hajime Nagase, Atsushi Nakajima, Hisahiko Sekihara, +2

Journal of Gastroenterology

NutritionGastrointestinal Peptide HormoneObesityMetabolic SyndromeBody Composition +16

Vagal‐Central Nervous System Interactions Modulate the Feeding Response to Peripheral Enterostatin

Qi Tian, Hajime Nagase, David A. York, +1

Obesity Research

Factors predicting the presence of small bowel lesions in patients with obscure gastrointestinal bleeding

Eiji Sakai, Hiroki Endo, Leo Taniguchi, +15

Digestive Endoscopy

Hepatic glucose-sensitive unit regulation of glucose-induced insulin secretion in rats

Hajime Nagase, Shuji Inoue, Katsuaki Tanaka, +2

Physiology & Behavior

Metabolic SyndromeGastrointestinal Peptide HormoneHepatologyLiver PhysiologyPhysiology +8