Otoferlin, Defective in a Human Deafness Form, Is Essential for Exocytosis at the Auditory Ribbon Synapse

Isabelle Roux, Saaïd Safieddine, Régis Nouvian, +11

Cell

NeuroanatomyMedicineAudiologyAuditory Ribbon SynapseArts +8

Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo

Raphaëlle Grifone, Josiane Demignon, Christophe Houbron, +5

Development

Single Six1 KoMrf ExpressionGeneticsSix1 GenesCell Specialization +17

Cubilin Is Essential for Albumin Reabsorption in the Renal Proximal Tubule

Sabine Amsellem, Jakub Gburek, Ghislaine Hamard, +6

Journal of the American Society of Nephrology

Megalin Drives InternalizationRenal PathologyAlbumin ReabsorptionCellular PhysiologyRenal Function +21

Lactadherin promotes VEGF-dependent neovascularization

Jean‐Sébastien Silvestre, Clotilde Théry, Ghislaine Hamard, +14

Nature Medicine

Vegf-dependent NeovascularizationAngiogenesisOphthalmologyVascular BiologyNeovascularization +4

Targeted disruption of the hepcidin 1 gene results in severe hemochromatosis

Jeanne-Claire Lesbordes-Brion, Lydie Viatte, Myriam Bennoun, +6

Blood

Altered myogenesis in<i>Six1</i>-deficient mice

Christine Laclef, Ghislaine Hamard, Josiane Demignon, +3

Development

Muscle FunctionCellular PhysiologyEmbryologyTissue DevelopmentSkeletal Muscle +15

Targeted Inactivation of Serum Response Factor in the Developing Heart Results in Myocardial Defects and Embryonic Lethality

Ara Parlakian, David Tuil, Ghislaine Hamard, +6

Molecular and Cellular Biology

Cardiac MuscleHeart FailureEmbryonic LethalityCardiac Progenitor CellsCongenital Heart Anomaly +20

Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers

Sabine Colnot, Michiko Niwa‐Kawakita, Ghislaine Hamard, +7

Laboratory Investigation

Cancer PathologyFamilial Adenomatous PolyposisGeneticsMedicineEnvironmental Modifiers +7

Dystrophin gene transcribed from different promoters in neuronal and glial cells

Jamel Chelly, Ghislaine Hamard, Annette Koulakoff, +3

Nature

Transcriptional RegulationMolecular NeuroscienceDystrophin GeneDifferent PromotersGenetics +7

Intralysosomal Cystine Accumulation in Mice Lacking Cystinosin, the Protein Defective in Cystinosis

Stéphanie Cherqui, Caroline Sevin, Ghislaine Hamard, +8

Molecular and Cellular Biology

UrologyProtein DefectivePhysiologyMice Lacking CystinosinIntralysosomal Cystine Accumulation +8