Inhibition of Extracellular Signal–Regulated Kinase Enhances Ischemia/Reoxygenation–Induced Apoptosis in Cultured Cardiac Myocytes and Exaggerates Reperfusion Injury in Isolated Perfused Heart

Tianli Yue, Chuanlin Wang, Juan-Li Gu, +7

Circulation Research

Cardiac MuscleHeart FailureApoptosisCell DeathCellular Physiology +18

Physical, Morphological and Functional Differences between pH 5.8 and 7.4 Aggregates of the Alzheimer's Amyloid Peptide A β

Stephen Wood, Beverly E. Maleeff, Timothy K. Hart, +1

Journal of Molecular Biology

Neurodegenerative DiseasesAlzheimer's DiseaseFunctional DifferencesBiochemistryProtein Folding +6

Preclinical efficacy and safety of mepolizumab (SB-240563), a humanized monoclonal antibody to IL-5, in cynomolgus monkeys

Timothy K. Hart, Richard M. Cook, Parnian Zia‐Amirhosseini, +10

Journal of Allergy and Clinical Immunology

Autoimmune DiseaseCynomolgus MonkeysMedicineImmunologyPreclinical Efficacy +7

Selective Inhibition of Aβ Fibril Formation

Stephen Wood, Lauri MacKenzie, Beverly E. Maleeff, +2

Journal of Biological Chemistry

Extracellular Signal-regulated Kinase Plays an Essential Role in Hypertrophic Agonists, Endothelin-1 and Phenylephrine-induced Cardiomyocyte Hypertrophy

Tianli Yue, Juan-Li Gu, Chuanlin Wang, +8

Journal of Biological Chemistry

Molecular and pharmacological characterization of genes encoding urotensin‐II peptides and their cognate G‐protein‐coupled receptors from the mouse and monkey

Nabil A. Elshourbagy, Stephen A. Douglas, Usman Shabon, +8

British Journal of Pharmacology

Molecular PharmacologyUrologyMolecular PhysiologySignal TransductionPharmacological Characterization +13

Exact kinetic analysis of passive transport across a polarized confluent MDCK cell monolayer modeled as a single barrier

Thuy Tran, Tracy L. Gales, Beverly E. Maleeff, +6

Journal of Pharmaceutical Sciences

EngineeringPassive TransportDiffusion ResistanceMembrane TransportTransport Phenomena +9

The Locations of Collagens with Different Thermal Stabilities in Fibrils of Bovine Reticular Dermis

Paul L. Kronick, Beverly E. Maleeff, Robert J. Carroll

Connective Tissue Research

Purification and characterization of fully functional human osteoclast precursors

Ian E. James, Robert A. Dodds, E. Lee-Rykaczewski, +6

Journal of Bone and Mineral Research

Whale DentineHomogeneous Cell PopulationImmunocytochemical TechniqueSclerostinBone Morphogenic Protein +11

Mutational effects on inclusion body formation in the periplasmic expression of the immunoglobulin VL domain REI

Winnie Chan, Larry R. Helms, Ian Brooks, +6

Folding and Design

ImmunogeneticsSignal TransductionAutoimmune DiseasePeriplasmic ExpressionProtein Expression +10