Allosite: a method for predicting allosteric sites

Wenkang Huang, Shaoyong Lu, Zhimin Huang, +8

Bioinformatics

Crystal Structures of PI3Kα Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design

Yanlong Zhao, Xi Zhang, Ying‐Yi Chen, +11

ACS Medicinal Chemistry Letters

Crystal StructureMolecular BiologyTumor BiologySignaling PathwayCancer Cell Biology +19

A Novel Small-Molecule Aurora Kinase Inhibitor Attenuates Breast Tumor–Initiating Cells and Overcomes Drug Resistance

Fei-Meng Zheng, Zi-Jie Long, Zhi-Jie Hou, +13

Molecular Cancer Therapeutics

Mangiferin Induces Apoptosis by Regulating Bcl-2 and Bax Expression in the CNE2 Nasopharyngeal Carcinoma Cell Line

Lili Pan, Ai-Yan Wang, Yongqi Huang, +2

Asian Pacific Journal of Cancer Prevention

Chemoprevention StrategyApoptosisImmunologyCell DeathBax Expression +14

Double-Layered Microcapsules Significantly Improve the Long-Term Effectiveness of Essential Oil

Ting Zhang, Yu Luo, Mingxing Wang, +4

Polymers

A novel model system for studying the double-edged roles of nitric oxide production in pancreatic cancer growth and metastasis

Bailiang Wang, Daoyan Wei, Vanessa E Crum, +6

Oncogene

Nitric Oxide ProductionPancreatic CancerReactive Nitrogen SpecieMedicineNitrosative Stress +8

Design, synthesis and bioevaluation of N-trisubstituted pyrimidine derivatives as potent aurora A kinase inhibitors

Yu Luo, Yan-Qiu Deng, Jing Wang, +6

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryBioorganic ChemistryBiochemistryNatural Sciences +9

Palladium-catalyzed Suzuki cross-coupling of N′-tosyl arylhydrazines

Jin‐Biao Liu, Hui Yan, Hui‐Xuan Chen, +3

Chemical Communications

Design, Synthesis, and Biological Evaluation of Substituted Pyrimidines as Potential Phosphatidylinositol 3-Kinase (PI3K) Inhibitors

Jiquan Zhang, Yongjie Luo, Yanshi Xiong, +8

Journal of Medicinal Chemistry

Target CompoundsPharmacotherapyChemical BiologyPharmaceutical ChemistryPre-clinical Pharmacology +20

Aurora A Kinase Inhibitor AKI603 Induces Cellular Senescence in Chronic Myeloid Leukemia Cells Harboring T315I Mutation

Le-Xun Wang, Jundan Wang, Jia-Jie Chen, +9

Scientific Reports