Siân H. Leech - Concepedia

Concepedia

Author

Siân H. Leech

University Hospital of Zurich

Also Known As

S H Leech, S Leech, S. H. Leech, Sian Leech, Siân H. Leech

11

Publications

1.1K

Citations

8

H-Index

35

Concepts

All Affiliations

University Hospital of Zurich University of Manchester University of Sheffield

SH

About

Siân H. Leech is an author at University Hospital of Zurich specializing in medicine, cell biology, and cancer research.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	6	6	865
2	Cell Biology	5	5	833
3	Natural Sciences	2	2	115
4	Biochemistry	1	1	32
5	Chemical Biology	1	1	32

Siân H. Leech

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8

Publications

1.1K

Citations

8

H-Index

	Year	Citations
A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy. Robert A. Olie, Ana Paula Simões‐Wüst, Bettina Baumann, PubMed Apoptosis ProteinApoptosisCell DeathNuclear CondensationSurvivin Mrna	2000	492
A novel bispecific antisense oligonucleotide inhibiting both bcl-2 and bcl-xL expression efficiently induces apoptosis in tumor cells. Uwe Zangemeister‐Wittke, Siân H. Leech, Robert A. Olie, PubMed ApoptosisImmunologyCell DeathTumor CellsImmunotherapy	2000	155
Activity of a Novel bcl-2/bcl-xL-Bispecific Antisense Oligonucleotide Against Tumors of Diverse Histologic Origins Oliver Gautschi, Stefan Tschopp, Robert A. Olie, JNCI Journal of the National Cancer Institute	2001	149
Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the pro-apoptotic protein Bak Gareth Griffiths, Bernard M. Corfe, Peter Savory, Oncogene Cellular Damage SignalsProtein FunctionSignal TransductionSignaling PathwayNatural Sciences	2001	83
Upregulation of BAK by butyrate in the colon is associated with increased Sp3 binding Haridasan Chirakkal, Siân H. Leech, Karen E. Brookes, Oncogene Signal TransductionSignaling PathwayMucosal ImmunologyIncreased Sp3 BindingPathology	2006	69
bcl-xl antisense treatment induces apoptosis in breast carcinoma cells Ana Paula Simões‐Wüst, Robert A. Olie, Oliver Gautschi, International Journal of Cancer	2000	65
Proteomic analyses of intermediate filaments reveals cytokeratin8 is highly acetylated – implications for colorectal epithelial homeostasis Siân H. Leech, Caroline A. Evans, Leila Shaw, PROTEOMICS Histone DeacetylasesPathologyProteomic TechnologySignaling PathwayFlat Mucosa	2008	34
The application of a hypothesis-driven strategy to the sensitive detection and location of acetylated lysine residues John R. Griffiths, Richard D. Unwin, Caroline A. Evans, Journal of the American Society for Mass Spectrometry Sensitive DetectionMolecular BiologyChemical BiologyHypothesis-driven MethodProtein Purification	2007	32

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