Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone.

Roberto Bolli, Brijeshkumar S. Patel, Mohamed O. Jeroudi, +2

Journal of Clinical Investigation

Heart FailurePbn Adduct ProductionLipid PeroxidationRedox BiologyOxidative Stress +16

Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial "stunning" is a manifestation of reperfusion injury.

Roberto Bolli, Mohamed O. Jeroudi, Brijeshkumar S. Patel, +4

Circulation Research

Heart FailureAntioxidant TherapyPbn Adduct ProductionCardiovascular ToxicityRedox Biology +14

Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog.

R Bolli, Mohamed O. Jeroudi, Brijeshkumar S. Patel, +4

Proceedings of the National Academy of Sciences

Oxygen-derived Free RadicalsHeart FailureLipid PeroxidationRedox BiologyOxidative Stress +19

Oxygen- and carbon-centered free radical formation during carbon tetrachloride metabolism. Observation of lipid radicals in vivo and in vitro.

Paul B. McCay, E K Lai, J. Lee Poyer, +2

Journal of Biological Chemistry

Reactive free radical generation in vivo in heart and liver of ethanol-fed rats: correlation with radical formation in vitro.

Lester A. Reinke, E K Lai, Coit M. DuBose, +1

Proceedings of the National Academy of Sciences

Lipid PeroxidationOxidative StressLow-fat DietHepatotoxicityHealth Sciences +16

Acquisition of increased hormone sensitivity during in vitro adipocyte development.

C S Rubin, E K Lai, O M Rosen

Journal of Biological Chemistry

Reproductive BiologyHormone ResponsivenessAdipokinesInsulin SignalingMetabolic Syndrome +17

Singlet oxygen production associated with enzyme-catalyzed lipid peroxidation in liver microsomes

M. Margaret King, E K Lai, PB McCay

Journal of Biological Chemistry

Lipid PeroxidationMolecular BiologyRedox BiologySinglet Oxygen ProductionOxidative Stress +15

Confirmation of assignment of the trichloromethyl radical spin adduct detected by spin trapping during 13C-carbon tetrachloride metabolism , , , ,

J. Lee Poyer, Paul B. McCay, E K Lai, +2

Biochemical and Biophysical Research Communications

BiochemistryNatural SciencesRadical (Chemistry)Electron Paramagnetic ResonanceMolecular Biology +2

Oxidative stress modulates vascular smooth muscle cell phenotype via CTGF in thoracic aortic aneurysm

Emanuela Branchetti, Paolo Poggio, Rachana Sainger, +9

Cardiovascular Research

Dexamethasone regulates the beta-adrenergic receptor subtype expressed by 3T3 L1 preadipocytes and adipocytes.

E K Lai, O M Rosen, C S Rubin

Journal of Biological Chemistry

Beta-receptor PhenotypeGlucocorticoidInsulin SignalingObesityMolecular Pharmacology +22