E K Lai

Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap alpha-phenyl N-tert-butyl nitrone.

Roberto Bolli, Brijeshkumar S. Patel, Mohamed O. Jeroudi et al. · Journal of Clinical Investigation · 1988 · 686 citations · Full text

Heart Failure, Pbn Adduct Production, Lipid Peroxidation +18

Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial "stunning" is a manifestation of reperfusion injury.

Roberto Bolli, Mohamed O. Jeroudi, Brijeshkumar S. Patel et al. · Circulation Research · 1989 · 582 citations

Heart Failure, Antioxidant Therapy, Pbn Adduct Production +16

Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog.

R Bolli, Mohamed O. Jeroudi, Brijeshkumar S. Patel et al. · Proceedings of the National Academy of Sciences · 1989 · 472 citations · Full text

Oxygen-derived Free Radicals, Heart Failure, Lipid Peroxidation +21

Oxygen- and carbon-centered free radical formation during carbon tetrachloride metabolism. Observation of lipid radicals in vivo and in vitro.

Paul B. McCay, E K Lai, J. Lee Poyer et al. · Journal of Biological Chemistry · 1984 · 321 citations · Full text

Reactive free radical generation in vivo in heart and liver of ethanol-fed rats: correlation with radical formation in vitro.

Lester A. Reinke, E K Lai, Coit M. DuBose et al. · Proceedings of the National Academy of Sciences · 1987 · 237 citations · Full text

Lipid Peroxidation, Oxidative Stress, Low-fat Diet +18