Hypoglycemic Activity of the Fruit of the Momordica charantia in Type 2 Diabetic Mice.

Toshihiro Miura, Chisa Itoh, Naoki Iwamoto, +4

Journal of Nutritional Science and Vitaminology

NutritionDiabetic MiceMomordica Charantia L.Insulin SignalingOxidative Stress +15

GTP‐binding protein involvement in membrane currents evoked by carbachol and histamine in guinea‐pig ileal muscle.

S. Komori, Masaomi Kawai, Tadashi Takewaki, +1

The Journal of Physiology

Guinea‐pig Ileal MuscleGastrointestinal PharmacologyProtein InvolvementMembrane CurrentsCellular Physiology +18

Oscillations of receptor-operated cationic current and internal calcium in single guinea-pig ileal smooth muscle cells

S. Komori, Masaomi Kawai, Pierre Pacaud, +2

Pflügers Archiv - European Journal of Physiology

Muscle FunctionKinesiologyMolecular PhysiologyNeurophysiologyPhysiology +6

Antioxidant enzymatically modified isoquercitrin or melatonin supplementation reduces oxidative stress-mediated hepatocellular tumor promotion of oxfendazole in rats

Jihei Nishimura, Yukie Saegusa, Yasuaki Dewa, +7

Archives of Toxicology

BiochemistryMedicineLipid PeroxidationHepatotoxicityAnti-cancer Agent +4

Involvement of oxidative stress in hepatocellular tumor-promoting activity of oxfendazole in rats

Yasuaki Dewa, Jihei Nishimura, Masako Muguruma, +6

Archives of Toxicology

MedicineLiver PhysiologyHepatocellular Tumor-promoting ActivityLipid PeroxidationPathology +7

Elevation of cell proliferation via generation of reactive oxygen species by piperonyl butoxide contributes to its liver tumor-promoting effects in mice

Masaomi Kawai, Yukie Saegusa, Yasuaki Dewa, +7

Archives of Toxicology

Tumor BiologyRedox RegulatorPiperonyl ButoxideMedicineLiver Physiology +12

Global DNA methylation screening of liver in piperonyl butoxide-treated mice in a two-stage hepatocarcinogenesis model

Atsunori Yafune, Masaomi Kawai, Megu Itahashi, +4

Toxicology Letters

Piperonyl Butoxide-treated MiceHepatologyEpigenetic ChangeLiver PhysiologyGenetics +9

Threshold dose of piperonyl butoxide that induces reactive oxygen species-mediated hepatocarcinogenesis in rats

Masako Muguruma, Masaomi Kawai, Yasuaki Dewa, +8

Archives of Toxicology

Threshold DoseHepatologyPiperonyl ButoxideMedicineLiver Physiology +10

δ-Tocotrienol suppresses tumorigenesis by inducing apoptosis and blocking the COX-2/PGE2 pathway that stimulates tumor–stromal interactions in colon cancer

Sayori Wada, Yuji Naito, Yuko Matsushita, +7

Journal of Functional Foods

Tumor BiologyChemoprevention StrategyMedicineApoptosisPharmacology +10

Crosstalk between PTEN/Akt2 and TGFβ signaling involving EGF receptor down‐regulation during the tumor promotion process from the early stage in a rat two‐stage hepatocarcinogenesis model

Eriko Taniai, Masaomi Kawai, Yasuaki Dewa, +6

Cancer Science

Tensin HomologTgfbeta ReceptorTumor BiologySignaling PathwayReceptor Tyrosine Kinase +17