Tim F. Tam

Design and synthesis of 4H-3,1-benzoxazin-4-ones as potent alternate substrate inhibitors of human leukocyte elastase

Allen Krantz, Robin W. Spencer, Tim F. Tam et al. · Journal of Medicinal Chemistry · 1990 · 267 citations · Full text

1,2,4-Thiadiazole: A novel Cathepsin B inhibitor

Régis Leung-Toung, Jolanta Wodzinska, Wanren Li et al. · Bioorganic & Medicinal Chemistry · 2003 · 78 citations

Molecular Pharmacology, Medicinal Chemistry, Medicine +5

Ynenol lactones: synthesis and investigation of reactions relevant to their inactivation of serine proteases

Robin W. Spencer, Tim F. Tam, Everton M. Thomas et al. · Journal of the American Chemical Society · 1986 · 59 citations

Molecular Sciences, Biosynthesis, Bioorganic Chemistry +15

Synthesis of 3-Substituted Bicyclic Imidazo[1,2-<i>d</i>][1,2,4]thiadiazoles and Tricyclic Benzo[4,5]imidazo[1,2-<i>d</i>][1,2,4]thiadiazoles

Régis Leung-Toung, Tim F. Tam, Yanqing Zhao et al. · The Journal of Organic Chemistry · 2005 · 33 citations

Heterocyclic, Selective Methylation, Biochemistry +8

Intriguing structure-activity relations underlie the potent inhibition of HIV protease by norstatine-based peptides

Tim F. Tam, Julie Carriere, Isaiah MacDonald et al. · Journal of Medicinal Chemistry · 1992 · 32 citations · Full text

Peptide Engineering, Immunology, Altmetric Attention Score +25