Jörg Czech

Growth Inhibition With Reversible Cell Cycle Arrest of Carcinoma Cells by Flavone L86-8275

Gurmeet Kaur, M Stetler-Stevenson, S Sebers et al. · JNCI Journal of the National Cancer Institute · 1992 · 349 citations

Flavopiridol (L86 8275; NSC 649890), a new kinase inhibitor for tumor therapy

H.H. Sedlacek, Jörg Czech, Ramachandra Naik et al. · International Journal of Oncology · 1996 · 277 citations

Chemoprevention Strategy, Pharmacotherapy, New Synthetic Flavone +18

Tumor-selective prodrug activation by fusion protein-mediated catalysis.

Klaus Bosslet, Jörg Czech, Dieter Hoffmann · PubMed · 1994 · 127 citations

Drug Targeting, Oncology, Tumor-selective Prodrug Activation +13

Probing the Subpockets of Factor Xa Reveals Two Binding Modes for Inhibitors Based on a 2-Carboxyindole Scaffold:  A Study Combining Structure-Activity Relationship and X-ray Crystallography

Marc Nazaré, David W. Will, Hans Matter et al. · Journal of Medicinal Chemistry · 2005 · 117 citations · Full text

X-ray Crystallography, Drug Target, Molecular Biology +17

Molecular and functional characterisation of a fusion protein suited for tumour specific prodrug activation

Klaus Bosslet, Jörg Czech, Peter Lorenz et al. · British Journal of Cancer · 1992 · 102 citations · Full text

Functional Characterisation, Protein Function, Medicine +11