Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study

Yasuo Ohkubo, Hideki Kishikawa, Eiichi Araki, +6

Diabetes Research and Clinical Practice

Metabolic SyndromeDiabetes ManagementCardiovascular DiseaseIntensive Insulin TherapyInsulin Management +8

Evaluation of Urinary 8-Hydroxydeoxy-Guanosine as a Novel Biomarker of Macrovascular Complications in Type 2 Diabetes

Takeshi Nishikawa, Takayuki Sasahara, Shinsuke Kiritoshi, +10

Diabetes Care

Cost-effectiveness of intensive insulin therapy for type 2 diabetes: a 10-year follow-up of the Kumamoto study

Nakayasu Wake, Akinori Hisashige, Takafumi Katayama, +5

Diabetes Research and Clinical Practice

ObesityMetabolic SyndromeDiabetes ManagementHealth EconomicsIntensive Insulin Therapy +9

Involvement of bradykinin in acute exercise-induced increase of glucose uptake and GLUT-4 translocation in skeletal muscle: Studies in normal and diabetic humans and rats

Tetsuya Taguchi, Hideki Kishikawa, Hiroyuki Motoshima, +7

Metabolism

Metabolic SyndromeMuscle FunctionKinesiologyGlut-4 TranslocationSkeletal Muscle +10

Impact of Natural IRS-1 Mutations on Insulin Signals: Mutations of IRS-1 in the PTB Domain and Near SH2 Protein Binding Sites Result in Impaired Function at Different Steps of IRS-1 Signaling

Ryohei Yoshimura, Eiichi Araki, Sachiko Ura, +9

Diabetes

Molecular BiologyInsulin ReceptorInsulin SignalingSignaling PathwayHuman Insulin Receptor +17

Possible Involvement of Atypical Protein Kinase C(PKC) in Glucose-Sensitive Expression of the Human Insulin Gene: DNA-Binding Activity and Transcriptional Activity of Pancreatic and Duodenal Homeobox Gene-1(PDX-1) Are Enhanced via Calphostin C-Sensitive but Phorbol 12-Myristate 13-Acetate(PMA) and Goe 6976-Insensitive Pathway.

Noboru Furukawa, T. Shirotani, Eiichi Araki, +8

Endocrine Journal

Osteopontin Expression of Circulating T Cells and Plasma Osteopontin Levels are Increased in Relation to Severity of Heart Failure

Hirofumi Soejima, Atsushi Irie, Takashi Fukunaga, +9

Circulation Journal

Hepatoid adenocarcinoma of the gallbladder

Hiroshi Nakashima, Kazumitsu Nagafuchi, Hiroshi Satoh, +4

Journal of Hepato-Biliary-Pancreatic Surgery

HepatologyBiliary TractBiliary CancerLiver PhysiologySurgical Pathology +7

Increased Serum Matrix Metalloproteinase-1 Concentration Predicts Advanced Left Ventricular Remodeling in Patients With Acute Myocardial Infarction.

Hirofumi Soejima, Hisao Ogawa, Tomohiro Sakamoto, +11

Circulation Journal

CardiomyopathyHeart FailureCardiovascular DiseaseAtherosclerosisMyocardial Infarction +10

Emergency decompression of bile duct in acute obstructive suppurative 3 cholangitis by duodenoscopic cannulation: A lifesaving procedure

Seiyo Ikeda, Masao Tanaka, Hideaki Itoh, +2

World Journal of Surgery