Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity

Dmitry M. Shayakhmetov, Anuj Gaggar, Shaoheng Ni, +2

Journal of Virology

Viral PathogenesisImmunologyPathologyViral Structural ProteinImmunotherapy +21

Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

Alan L. Parker, Simon N. Waddington, Campbell G. Nicol, +9

Blood

Directed Evolution Generates a Novel Oncolytic Virus for the Treatment of Colon Cancer

Irene Kuhn, Paul Harden, Maxine Bauzon, +10

PLoS ONE

Analysis of Adenovirus Sequestration in the Liver, Transduction of Hepatic Cells, and Innate Toxicity after Injection of Fiber-Modified Vectors

Dmitry M. Shayakhmetov, Zong-Yi Li, Shaoheng Ni, +1

Journal of Virology

Adenovirus-Platelet Interaction in Blood Causes Virus Sequestration to the Reticuloendothelial System of the Liver

Daniel Stone, Ying Liu, Dmitry M. Shayakhmetov, +3

Journal of Virology

Viral PathogenesisImmunologyPathologyGene DeliveryImmunotherapy +18

Baculovirus-based Vaccination Vectors Allow for Efficient Induction of Immune Responses Against Plasmodium falciparum Circumsporozoite Protein

Robert Strauss, Andreas Hüser, Shaoheng Ni, +5

Molecular Therapy

A Tumor-Targeted and Conditionally Replicating Oncolytic Adenovirus Vector Expressing TRAIL for Treatment of Liver Metastases

Pavel Sova, Xiao-Wei Ren, Shaoheng Ni, +4

Molecular Therapy

Targeting of adenovirus vectors to tumor cells does not enable efficient transduction of breast cancer metastases.

Dmitry M. Shayakhmetov, Zong Yi Li, Shaoheng Ni, +1

PubMed

Breast Cancer MetastasisBreast OncologyImmunologyEfficient TransductionTumor Biology +15

Evaluation of Biodistribution and Safety of Adenovirus Vectors Containing Group B Fibers After Intravenous Injection into Baboons

Shaoheng Ni, Kathrin M. Bernt, Anuj Gaggar, +3

Human Gene Therapy

Development and Assessment of Human Adenovirus Type 11 as a Gene Transfer Vector

Daniel Stone, Shaoheng Ni, Zong-Yi Li, +5

Journal of Virology

ImmunologyPathologyImmunotherapyAd11 GenomesAdenovirus Vectors +14