Activity of durvalumab plus olaparib in metastatic castration-resistant prostate cancer in men with and without DNA damage repair mutations

Fatima Karzai, David James VanderWeele, Ravi A. Madan, +24

Journal for ImmunoTherapy of Cancer

Sunitinib in patients with chemotherapy-refractory thymoma and thymic carcinoma: an open-label phase 2 trial

Anish Thomas, Arun Rajan, Arlene Berman, +15

The Lancet Oncology

Open-label Phase 2OncologyClinical TrialsImmune Checkpoint InhibitorDermatology +4

Fumarate Hydratase Deficiency in Renal Cancer Induces Glycolytic Addiction and Hypoxia-Inducible Transcription Factor 1α Stabilization by Glucose-Dependent Generation of Reactive Oxygen Species

Sunil Sudarshan, Carole Sourbier, Hye-Sik Kong, +12

Molecular and Cellular Biology

Metabolic RemodelingReactive Oxygen SpeciesRedox BiologyOxidative StressRedox Regulator +20

Phase II Study of Belinostat in Patients With Recurrent or Refractory Advanced Thymic Epithelial Tumors

Giuseppe Giaccone, Arun Rajan, Arlene Berman, +9

Journal of Clinical Oncology

Phase II Trial of Bevacizumab, Thalidomide, Docetaxel, and Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer

Yang-Min Ning, James L. Gulley, Philip M. Arlen, +14

Journal of Clinical Oncology

UrologyOncologyPhase Ii TrialPharmacologyClinical Trials +10

Phase I Study of Cabozantinib and Nivolumab Alone or With Ipilimumab for Advanced or Metastatic Urothelial Carcinoma and Other Genitourinary Tumors

Andrea B. Apolo, Rosa Nadal, Daniel M. Girardi, +32

Journal of Clinical Oncology

Dynamic Tyrosine Phosphorylation Modulates Cycling of the HSP90-P50CDC37-AHA1 Chaperone Machine

Wanping Xu, Mehdi Mollapour, Chrisostomos Prodromou, +11

Molecular Cell

Signal TransductionBiochemistryNatural SciencesHsp90-p50cdc37-aha1 Chaperone MachineMolecular Biology +5

Interactions between Shh, Sostdc1 and Wnt signaling and a new feedback loop for spatial patterning of the teeth

Sung Won Cho, Sungwook Kwak, Thomas E. Woolley, +7

Development

Wnt SignalingSpatial PatterningSonic HedgehogEmbryologySostdc1 Act +16

Cixutumumab for patients with recurrent or refractory advanced thymic epithelial tumours: a multicentre, open-label, phase 2 trial

Arun Rajan, Corey A. Carter, Arlene Berman, +17

The Lancet Oncology

Cancer ImmunosurveillanceMedicineImmunologyImmune Checkpoint InhibitorCancer Treatment +3

Entinostat plus Pembrolizumab in Patients with Metastatic NSCLC Previously Treated with Anti–PD-(L)1 Therapy

Matthew D. Hellmann, Pasi A. Jänne, Mateusz Opyrchal, +17

Clinical Cancer Research