The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.

Bertrand Le Douarin, Christina Zechel, J.M. Garnier, +7

The EMBO Journal

N-terminal PartSignal TransductionSignaling PathwayLigand-dependent Activation FunctionNatural Sciences +9

A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

Bertrand Le Douarin, Anders Lade Nielsen, Jean‐Marie Garnier, +4

The EMBO Journal

Tif1 AlphaChromatinTranscriptional RegulationTif1 BetaSignal Transduction +13

Interference of nonsense mutations with eukaryotic messenger RNA stability.

Régine Losson, F. Lacroute

Proceedings of the National Academy of Sciences

Yeast Ura 3GeneticsRna SplicingGenomic MechanismMolecular Biology +16

Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.

Elmar vom Baur, Christina Zechel, David M. Heery, +7

The EMBO Journal

Transcriptional RegulationSignal TransductionSignaling PathwayMolecular PathwayDifferential Ligand-dependent Interactions +8

Heterochromatin Formation in Mammalian Cells

Anders Lade Nielsen, Mustapha Oulad‐Abdelghani, J A Ortíz, +3

Molecular Cell

Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family

Anders Lade Nielsen, J A Ortíz, Jun You, +5

The EMBO Journal

Histone ModificationsEpigenetic ChangeGeneticsEpigeneticsTranscriptional Regulation +14

Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity.

Béatrice Durand, Michael A. Saunders, C. Gaudon, +3

The EMBO Journal

InflammationActivation Function 2Signal TransductionSignaling PathwayBiochemistry +11

Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma

Benjamin Herquel, Khalid Ouararhni, Konstantin Khetchoumian, +10

Proceedings of the National Academy of Sciences

PathologyHcc FormationCancer BiologyTumor BiologyTranscriptional Regulation +21

Mice lacking the transcriptional corepressor TIF1β are defective in early postimplantation development

Florence Cammas, Manuel Mark, Pascal Dollé, +3

Development

Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma

María Berdasco, Santiago Ropero, Fernando Setién, +7

Proceedings of the National Academy of Sciences

Histone ModificationsHuman NeuroblastomaEpigenetic ChangeGeneticsEpigenetic Inactivation +17