Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1

Miki Nishio, Kenichi Watanabe, Junko Sasaki, +16

Nature Cell Biology

Signal TransductionBiochemistryMedicineNatural SciencesMolecular Biology +9

TIE2-expressing monocytes as a diagnostic marker for hepatocellular carcinoma correlates with angiogenesis

Tokuhiro Matsubara, Tatsuya Kanto, Shoko Kuroda, +12

Hepatology

An angiotensin II type 1 receptor antagonist, olmesartan medoxomil, improves experimental liver fibrosis by suppression of proliferation and collagen synthesis in activated hepatic stellate cells

Nobuya Kurikawa, Miwa Suga, Shoko Kuroda, +2

British Journal of Pharmacology

Basic leucine zipper transcription factor, ATF-like (BATF) regulates epigenetically and energetically effector CD8 T-cell differentiation via Sirt1 expression

Shoko Kuroda, Maya Yamazaki, Manabu Abe, +3

Proceedings of the National Academy of Sciences

Impaired Fertility in Female Mice Lacking Urinary Trypsin Inhibitor

Hiroyuki Sato, Satoshi Kajikawa, Shoko Kuroda, +8

Biochemical and Biophysical Research Communications

InfertilityUrologyAndrologyFertilityFemale Infertility +9

Human blood dendritic cell antigen 3 (BDCA3)+ dendritic cells are a potent producer of interferon-λ in response to hepatitis C virus

Sachiyo Yoshio, Tatsuya Kanto, Shoko Kuroda, +13

Hepatology

Identification of a Human Clonogenic Progenitor with Strict Monocyte Differentiation Potential: A Counterpart of Mouse cMoPs

Shunsuke Kawamura, Nobuyuki Onai, Fuyuki Miya, +8

Immunity

Knockout MouseEmbryonic Stem CellCell LineageMouse CmopsDevelopmental Biology +8

Apoptosis-induced Decrease of Intrathyroidal CD4 ⁺ CD25 ⁺ Regulatory T Cells in Autoimmune Thyroid Diseases

Aiko Nakano, Mikio Watanabe, Takao Iida, +4

Thyroid

An IFN-γ-IL-18 Signaling Loop Accelerates Memory CD8+ T Cell Proliferation

Yoshiko Iwai, Hiroaki Hemmi, Olga Mizenina, +3

PLoS ONE

Adaptive Immune SystemT-regulatory CellImmune RegulationImmunologyImmunologic Mechanism +16

Association of enhanced activity of indoleamine 2,3-dioxygenase in dendritic cells with the induction of regulatory T cells in chronic hepatitis C infection

Koyo Higashitani, Tatsuya Kanto, Shoko Kuroda, +14

Journal of Gastroenterology

InflammationEnhanced ActivityViral HepatitisImmune RegulationImmunology +9