Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis

Ronggai Sun, Yasir A. W. Skeiky, Angelo Izzo, +15

Vaccine

Medical MicrobiologyPulmonary TuberculosisTuberculosis PreventionImmunologyPathogenesis +7

A population-based analysis of the longevity of SARS-CoV-2 antibody seropositivity in the United States

David Alfego, Adam Sullivan, Brian Poirier, +5

EClinicalMedicine

HspX‐mediated protection against tuberculosis depends on its chaperoning of a mycobacterial molecule

Jennifer L. Taylor, Agatha E. Wieczorek, Andrew Keyser, +6

Immunology and Cell Biology

BAT3 Regulates Mycobacterium tuberculosis Protein ESAT-6-Mediated Apoptosis of Macrophages

Ajay Grover, Angelo Izzo

PLoS ONE

Adaptive Immune SystemNitric OxideApoptosisImmunologyImmune Regulation +19

A multivalent combination of experimental antituberculosis DNA vaccines based on Ag85B and regions of difference antigens

Ajay Grover, Mir Fayaz Ahmed, Balwan Singh, +3

Microbes and Infection

VaccinationVaccine DevelopmentMedicineVaccine TargetImmunology +9

Kinetics of the Immune Response Profile in Guinea Pigs after Vaccination with<i>Mycobacterium bovis</i>BCG and Infection with<i>Mycobacterium tuberculosis</i>

Ajay Grover, Jennifer L. Taylor, JoLynn Troudt, +5

Infection and Immunity

Supplementation with RD antigens enhances the protective efficacy of BCG in tuberculous mice

Mamta Kalra, Ajay Grover, Neena Mehta, +7

Clinical Immunology

Pulmonary TuberculosisProtective EfficacyAdaptive Immune SystemMedicineImmunology +5

Utility of a combination of RD1 and RD2 antigens as a diagnostic marker for tuberculosis

Mamta Kalra, G. K. Khuller, Ajay Grover, +3

Diagnostic Microbiology and Infectious Disease

Pulmonary TuberculosisEngineeringMedicinePathogenesisImmunology +10

Mycobacterial infection induces the secretion of high-mobility group box 1 protein

Ajay Grover, Jennifer Taylor, JoLynn Troudt, +4

Cellular Microbiology

ImmunologyPathologyInnate ImmunityImmune SystemImmunotherapy +19

Expression and purification of the Mycobacterium tuberculosis complex-restricted antigen CFP21 to study its immunoprophylactic potential in mouse model

Ajay Grover, Mir Fayaz Ahmed, Indu Verma, +2

Protein Expression and Purification

Pulmonary TuberculosisPathogenesisImmunologyImmunoprophylactic PotentialTuberculosis +5