Degradation of the fluoroquinolone enrofloxacin by the brown rot fungus Gloeophyllum striatum: identification of metabolites

Heinz-Georg Wetzstein, N. Schmeer, W. Karl

Applied and Environmental Microbiology

Industrial MycologyBiosynthesisAntifungal AgentBiochemistryBioassay-guided Isolation +11

Outlines of an “exploding” network of metabolites generated from the fluoroquinolone enrofloxacin by the brown rot fungus Gloeophyllum striatum

W. Karl, Josef Schneider, Heinz-Georg Wetzstein

Applied Microbiology and Biotechnology

BiologyIndustrial MycologyBiochemistryNatural SciencesMedicinal Fungi +4

Patterns of metabolites produced from the fluoroquinolone enrofloxacin by basidiomycetes indigenous to agricultural sites

Heinz-Georg Wetzstein, Josef Schneider, W. Karl

Applied Microbiology and Biotechnology

BiochemistryMedicineMycotoxin FormationSecondary MetaboliteFluoroquinolone Enrofloxacin +4

Extracellular serine proteases from Stenotrophomonas maltophilia: Screening, isolation and heterologous expression in E. coli

Doris Ribitsch, Sonja Heumann, W. Karl, +12

Journal of Biotechnology

Protease InhibitorsE. ColiBiochemistryVirulence FactorExtracellular Serine Proteases +5

Utility of the Ammonia‐Free Birch Reduction of Electron‐Deficient Pyrroles: Total Synthesis of the 20S Proteasome Inhibitor, <i>clasto</i>‐Lactacystin β‐Lactone

Timothy J. Donohoe, Herman O. Sintim, Leena Sisangia, +4

Chemistry - A European Journal

EngineeringEnolate MethylationOrganic ChemistryChemistryPharmaceutical Chemistry +15

Pharmacokinetics of nisoldipine. III. Biotransformation of nisoldipine in rat, dog, monkey, and man.

D. Scherling, W. Karl, G. Ahr, +2

PubMed

Unchanged DrugPharmacokinetic ModelingHepatologyHealth SciencesMedicine +13

C-terminal truncation of a metagenome-derived detergent protease for effective expression in E. coli

Doris Ribitsch, W. Karl, Ruth Birner‐Gruenberger, +7

Journal of Biotechnology

E. ColiProtein ExpressionNatural SciencesMedicineProtein Biosynthesis +8

Biotransformation of nimodipine in rat, dog, and monkey.

D. Scherling, K Bühner, Holger Krause, +2

PubMed

Molecular PharmacologyMethyl GroupUrologyPharmacological StudyMedicine +10

Development of an Efficient and Stereoselective Manufacturing Route to Idoxifene

W. Karl, Mark A. Armitage, Richard K. Bellingham, +9

Organic Process Research & Development

EngineeringOrganic ChemistryChemistryChemical EngineeringMedicinal Chemistry +16

Nitrendipine: identification and synthesis of main metabolites.

H. Meyer, D. Scherling, W. Karl

PubMed

Pyridine 2Medicinal ChemistryPharmacological StudyBiochemistryMedicine +11