Peginterferon Alfa-2a plus Ribavirin versus Interferon Alfa-2a plus Ribavirin for Chronic Hepatitis C in HIV-Coinfected Persons

Raymond T. Chung, Janet Andersen, Paul A. Volberding, +11

New England Journal of Medicine

Charting cellular identity during human in vitro β-cell differentiation

Adrian Veres, Aubrey L. Faust, Henry L. Bushnell, +9

Nature

Human CellDevelopmental BiologyCellular IdentityCell DifferentiationCell Fate Determination +5

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation

Weijun Shen, Brandon L. Taylor, Qihui Jin, +27

Nature Communications

Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double-blind trial

Jinlin Hou, You‐Kuan Yin, Dao-zhen Xu, +18

Hepatology

Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells

Peng Wang, Esra Karaköse, Hongtao Liu, +16

Cell Metabolism

Robust ReplicationSignal TransductionSignaling PathwayCell RegulationReceptor Tyrosine Kinase +6

Marginal mass islet transplantation with autologous mesenchymal stem cells promotes long-term islet allograft survival and sustained normoglycemia

Mario G. Solari, Suganya Srinivasan, Imene Boumaza, +3

Journal of Autoimmunity

Regenerative MedicineIslet TransplantationTransplantationMedicineStem Cell Transplantation +9

Survey of the Human Pancreatic β-Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D1 in Enhancing Human β-Cell Replication and Function In Vivo

Nathalie Fiaschi‐Taesch, Todd A. Bigatel, Brian M. Sicari, +7

Diabetes

Small-Molecule Inducer of β Cell Proliferation Identified by High-Throughput Screening

Weijun Shen, Matthew S. Tremblay, V. Deshmukh, +17

Journal of the American Chemical Society

Cell ProliferationCell GrowthInsulin SignalingSmall MoleculesSignaling Pathway +15

Survival of Microencapsulated Islets at 400 Days Posttransplantation in the Omental Pouch of NOD Mice

Tsunehiro Kobayashi, Yukio Aomatsu, Hiroo Iwata, +7

Cell Transplantation

Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133

Yahu A. Liu, Qihui Jin, Yefen Zou, +38

Journal of Medicinal Chemistry