E. Laurensse

Uridine-induced hypothermia in mice and rats in relation to plasma and tissue levels of uridine and its metabolites

Godefridus J. Peters, C.J. van Groeningen, E. Laurensse et al. · Cancer Chemotherapy and Pharmacology · 1987 · 83 citations

Medicine, Physiology, Renal Inflammation +6

In vivo inhibition of the pyrimidine de novo enzyme dihydroorotic acid dehydrogenase by brequinar sodium (DUP-785; NSC 368390) in mice and patients.

Godefridus J. Peters, Gilberto Schwartsmann, Jorge Nadal et al. · PubMed · 1990 · 82 citations

Mitochondrial Pyrimidine, Pharmacotherapy, Experimental Pharmacology +18

Inhibition of pyrimidine de novo synthesis by DUP-785 (NSC 368390)

Godefridus J. Peters, S Sharma, E. Laurensse et al. · Investigational New Drugs · 1987 · 79 citations

Biosynthesis, Biochemistry, Natural Sciences +9

In vitro biochemical and in vivo biological studies of the uridine 'rescue' of 5-fluorouracil

Jerry van Dijk, E. Laurensse, CJ van Groeningen et al. · British Journal of Cancer · 1988 · 68 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +8

Reversal of 5-Fluorouracil-Induced Myelosuppression by Prolonged Administration of High-Dose Uridine

C.J. van Groeningen, Godefridus J. Peters, Alejandro Leyva et al. · JNCI Journal of the National Cancer Institute · 1989 · 67 citations

Therapeutic Drug Monitoring, Medicine, Hematology +10