Ryota Kunita

Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking

Shinji Hadano, Susanna C. Benn, Shigeru Kakuta et al. · Human Molecular Genetics · 2005 · 136 citations

Rab5 Guanine, Endosome Trafficking, Als2 Gene +16

The Rab5 Activator ALS2/alsin Acts as a Novel Rac1 Effector through Rac1-activated Endocytosis

Ryota Kunita, Asako Otomo, Hikaru Mizumura et al. · Journal of Biological Chemistry · 2007 · 89 citations · Full text

Als2 Gene Cause, Amyotrophic Lateral Sclerosis, Signal Transduction +15

Homo-oligomerization of ALS2 through Its Unique Carboxyl-terminal Regions Is Essential for the ALS2-associated Rab5 Guanine Nucleotide Exchange Activity and Its Regulatory Function on Endosome Trafficking

Ryota Kunita, Asako Otomo, Hikaru Mizumura et al. · Journal of Biological Chemistry · 2004 · 68 citations · Full text

Identification and localization of two genes on the chicken Z chromosome: implication of evolutionary conservation of the Z chromosome among avian species

Yasushi Saitoh, Akira Ogawa, Tetsuya Hori et al. · Chromosome Research · 1993 · 48 citations

Molecular Ecology, Cytogenetics, Z Chromosome +11

Defective relocalization of ALS2/alsin missense mutants to Rac1-induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation

Asako Otomo, Ryota Kunita, Kyoko Suzuki-Utsunomiya et al. · FEBS Letters · 2011 · 48 citations