Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2

Chun-ling Dai, Yong‐ju Liang, Yan-sheng Wang, +6

Cancer Letters

MedicinePhotocarcinogenesisMechanism Of ActionCell DeathAbcg2-overexpressing Cells +7

Secalonic Acid D induced leukemia cell apoptosis and cell cycle arrest of G1 with involvement of GSK-3β/β-catenin/c-Myc pathway

Jianye Zhang, Li-yang Tao, Yong‐ju Liang, +6

Cell Cycle

Vandetanib (Zactima, ZD6474) Antagonizes ABCC1- and ABCG2-Mediated Multidrug Resistance by Inhibition of Their Transport Function

Li-Sheng Zheng, Fang Wang, Yuhong Li, +10

PLoS ONE

Anthracenedione derivative 1403P-3 induces apoptosis in KB and KBv200 cells via reactive oxygen species-independent mitochondrial pathway and death receptor pathway

Jianye Zhang, Hai-ying Wu, Xue-kui Xia, +5

Cancer Biology & Therapy

Cediranib (recentin, AZD2171) reverses ABCB1- and ABCC1-mediated multidrug resistance by inhibition of their transport function

Li-yang Tao, Yong‐ju Liang, Fang Wang, +4

Cancer Chemotherapy and Pharmacology

Abcc1-mediated Multidrug ResistanceMedicinePharmacotherapyAntimicrobial ChemotherapyTransport Function +6

Blockade of Her2/<i>neu</i> Binding to Hsp90 by Emodin Azide Methyl Anthraquinone Derivative Induces Proteasomal Degradation of Her2/<i>neu</i>

Yan‐yan Yan, Li-Sheng Zheng, Xu Zhang, +11

Molecular Pharmaceutics

Chemoprevention StrategyMolecular RegulationPathologyNovel EmodinMolecular Pharmacology +14

Prognostic value of the multidrug resistance transporter ABCG2 gene polymorphisms in Chinese patients with de novo acute leukaemia

Fang Wang, Yong‐ju Liang, Xing-Ping Wu, +7

European Journal of Cancer

Hematological MalignancyAcute LeukaemiaHealth SciencesMedicineMixed-phenotype Acute Leukemia +10

Reversal of P-gp-mediated multidrug resistance by Bromotetrandrine in vivo is associated with enhanced accumulation of chemotherapeutical drug in tumor tissue.

Liming Chen, Yong-ju Liang, Xu Zhang, +6

PubMed

FG020326-loaded nanoparticle with PEG and PDLLA improved pharmacodynamics of reversing multidrug resistance in vitro and in vivo

Wen-jing Deng, Xiao-qiang YANG, Yong‐ju Liang, +4

Acta Pharmacologica Sinica

NanomedicineEngineeringPolymer-drug ConjugatePharmaceutical NanotechnologyMultidrug Resistance +6

Up-regulation of ABCB1/P-glycoprotein by escaping promoter hypermethylation indicates poor prognosis in hematologic malignancy patients with and without bone marrow transplantation

Cheng-Jun Shi, Fang Wang, Mei-feng Ren, +9

Leukemia Research

Hematological MalignancyTransplantationMedicinePromoter HypermethylationHematology +7