Elena Scotti

Crystal Structure of the Peroxisome Proliferator-Activated Receptor γ (PPARγ) Ligand Binding Domain Complexed with a Novel Partial Agonist: A New Region of the Hydrophobic Pocket Could Be Exploited for Drug Design

Roberta Montanari, Fulvio Saccoccia, Elena Scotti et al. · Journal of Medicinal Chemistry · 2008 · 97 citations · Full text

Crystal Structure, Other Ligands, Biochemistry +15

The LXR–Idol Axis Differentially Regulates Plasma LDL Levels in Primates and Mice

Cynthia Hong, Stephanie Marshall, Allison L. McDaniel et al. · Cell Metabolism · 2014 · 86 citations · Full text

Knockout Mouse, Molecular Regulation, Immunology +4

IDOL Stimulates Clathrin-Independent Endocytosis and Multivesicular Body-Mediated Lysosomal Degradation of the Low-Density Lipoprotein Receptor

Elena Scotti, Martino Calamai, Chris N. Goulbourne et al. · Molecular and Cellular Biology · 2013 · 78 citations · Full text

Proteinlipid Interaction, Clathrin-independent Endocytosis, Ldlr Degradation +18

Targeted Disruption of the Idol Gene Alters Cellular Regulation of the Low-Density Lipoprotein Receptor by Sterols and Liver X Receptor Agonists

Elena Scotti, Cynthia Hong, Yuko Yoshinaga et al. · Molecular and Cellular Biology · 2011 · 76 citations · Full text

Ldlr Degradation, Genetics, Fatty Liver Disease +18

Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor

Li Zhang, Ming Xu, Elena Scotti et al. · Journal of Lipid Research · 2013 · 60 citations · Full text