Class I Histone Deacetylase-Selective Novel Synthetic Inhibitors Potently Inhibit Human Tumor Proliferation

Jung‐Hyun Park, Yeonjoo Jung, Tai Young Kim, +7

Clinical Cancer Research

Trastuzumab inhibits the growth of human gastric cancer cell lines with HER2 amplification synergistically with cisplatin

Sun Kim, H.S. Kim, Yu Kyung Kim, +6

International Journal of Oncology

Tumor BiologyOncologyGastrointestinal OncologyMedicinePharmacology +11

Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells

Tai Young Kim, Hyun-Soon Jong, Sang‐Hyun Song, +6

Oncogene

Tumor BiologyTranscriptional RegulationGastric Cancer CellsMedicineGenetics +9

Gastric epithelial reactive oxygen species prevent normoxic degradation of hypoxia-inducible factor-1alpha in gastric cancer cells.

Tae You Kim, Hyun-Soon Jong, Tai Young Kim, +6

PubMed

Gastric Cancer CellsGastric Epithelial RosPathologyNormoxic DegradationRedox Biology +17

Cyclooxygenase-2 Inhibits Novel Ginseng Metabolite-Mediated Apoptosis

Hyung Woo Yim, Hyun-Soon Jong, Tai Young Kim, +7

Cancer Research

InflammationCox-2 EnzymeAnti-inflammatoryChemoprevention StrategyMedicine +10

Histone deacetylase inhibitor enhances 5-fluorouracil cytotoxicity by down-regulating thymidylate synthase in human cancer cells

Ju‐Hee Lee, Jung‐Hyun Park, Yeonjoo Jung, +4

Molecular Cancer Therapeutics

Histone Deacetylase InhibitorMolecular Regulation5-Fluorouracil CytotoxicityCancer BiologyTumor Biology +22

AKAP12/Gravin is inactivated by epigenetic mechanism in human gastric carcinoma and shows growth suppressor activity

Moon-Chang Choi, Hyun-Soon Jong, Tai Young Kim, +5

Oncogene

Cancer ResearchOncogenic AgentMedicinePathologyEpigenetic Mechanism +9

DLC-1, a GTPase-activating protein for Rho, is associated with cell proliferation, morphology, and migration in human hepatocellular carcinoma

Tai Young Kim, Hwang-Phill Kim, Hyun-Soon Jong, +3

Biochemical and Biophysical Research Communications

Cancer ResearchGtpase-activating ProteinHuman Hepatocellular CarcinomaMedicineLiver Physiology +9

Transforming Growth Factor-β1 Induces Apoptosis through Fas Ligand-independent Activation of the Fas Death Pathway in Human Gastric SNU-620 Carcinoma Cells

Sang Gyun Kim, Hyun-Soon Jong, Tae-You Kim, +3

Molecular Biology of the Cell

MitophagyApoptosisImmunologyCell DeathPathology +18

The Endogenous Ratio of Smad2 and Smad3 Influences the Cytostatic Function of Smad3

Sang Gyun Kim, Hyun‐Ah Kim, Hyun-Soon Jong, +5

Molecular Biology of the Cell

Cytostatic FunctionMolecular BiologyCellular PhysiologyTranscriptional RegulationSignaling Pathway +16