Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy

Michalis Papadakis, Gina Hadley, Maria Xilouri, +12

Nature Medicine

InflammationCell AutophagyAutophagyCell DeathNeuropharmacology +6

e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patients

Simon Nagel, Devesh Sinha, Diana J. Day, +21

International Journal of Stroke

Computed TomographyCerebrovascular DiseaseGround TruthVascular ImagingBrain Injury +20

Neuroprotection by Dimethyloxalylglycine following Permanent and Transient Focal Cerebral Ischemia in Rats

Simon Nagel, Michalis Papadakis, Ruoli Chen, +5

Journal of Cerebral Blood Flow & Metabolism

Cerebrovascular DiseaseSocial SciencesOxidative StressCerebral Vascular RegulationNeurovascular Disease +21

Appropriate NR1-NR1 Disulfide-linked Homodimer Formation Is Requisite for Efficient Expression of Functional, Cell Surface N-Methyl-D-aspartate NR1/NR2 Receptors

Michalis Papadakis, Lynda M. Hawkins, F. Anne Stephenson

Journal of Biological Chemistry

Differential interaction of NMDA receptor subtypes with the post‐synaptic density‐95 family of membrane associated guanylate kinase proteins

Sarah L. Cousins, Michalis Papadakis, A. Richard Rutter, +1

Journal of Neurochemistry

Improved regional cerebral blood flow is important for the protection seen in a mouse model of late phase ischemic preconditioning

Lisa Hoyte, Michalis Papadakis, Philip A. Barber, +1

Brain Research

Ischemic StrokeNeurophysiologyMedicineReperfusion InjuryPhysiology +13

Cerebral blood flow alteration in neuroprotection following cerebral ischaemia

Brad A. Sutherland, Michalis Papadakis, Ruoli Chen, +1

The Journal of Physiology

Cell DeathCerebrovascular DiseaseSocial SciencesBlood FlowCerebral Vascular Regulation +18

Roles of individual prolyl‐4‐hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice

Ruoli Chen, Simon Nagel, Michalis Papadakis, +5

The Journal of Physiology

Individual Prolyl‐4‐hydroxylase IsoformsOxidative StressCerebral Vascular RegulationNeurovascular DiseaseThrombosis +22

HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice

Ruoli L. Chen, Omolara O. Ogunshola, Kar Kheng Yeoh, +5

Journal of Neurochemistry

Mouse BrainsRedox BiologySocial SciencesOxidative StressNeuroinflammation +23

The role of the endoplasmic reticulum stress response following cerebral ischemia

Gina Hadley, Ain Neuhaus, Yvonne Couch, +7

International Journal of Stroke