William S. Sly

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

Alfonso González‐Noriega, Jeffrey H. Grubb, Venugopal D. Talkad et al. · The Journal of Cell Biology · 1980 · 741 citations · Full text

Bioorganic Chemistry, Molecular Biology, Enzymatic Modification +19

Expression of Hypoxia-Inducible Cell-Surface Transmembrane Carbonic Anhydrases in Human Cancer

Sergey V. Ivanov, Shu‐Yuan Liao, Alla Ivanova et al. · American Journal Of Pathology · 2001 · 675 citations · Full text

Tumor Biology, Tumor Microenvironment, Biochemistry +13

Carbonic anhydrase II deficiency identified as the primary defect in the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification.

William S. Sly, David Hewett‐Emmett, Michael P. Whyte et al. · Proceedings of the National Academy of Sciences · 1983 · 618 citations · Full text

Electrolyte Disorder, Carbonic Anhydrase Ii, Pathology +16

Phosphohexosyl components of a lysosomal enzyme are recognized by pinocytosis receptors on human fibroblasts.

A Kaplan, Daniel T. Achord, William S. Sly · Proceedings of the National Academy of Sciences · 1977 · 576 citations · Full text

Glycobiology, Phosphohexosyl Components, Charge Heterogeneity +18

HFE gene knockout produces mouse model of hereditary hemochromatosis

Xiao Zhou, Shunji Tomatsu, Robert E. Fleming et al. · Proceedings of the National Academy of Sciences · 1998 · 527 citations · Full text