Jeffrey H. Grubb

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

Alfonso González‐Noriega, Jeffrey H. Grubb, Venugopal D. Talkad et al. · The Journal of Cell Biology · 1980 · 742 citations · Full text

Life Sciences, Biochemistry, Cell Biology +13

Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers

Özlem Türeci, Uğur Şahin, Evi Vollmar et al. · Proceedings of the National Academy of Sciences · 1998 · 363 citations

Medicine, Molecular Biology, Oncology +15

Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells

Douglas A. Whittington, Abdül Waheed, Barbara Ulmasov et al. · Proceedings of the National Academy of Sciences · 2001 · 332 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells.

Akihiko Oshima, Catherine M. Nolan, John W. Kyle et al. · Journal of Biological Chemistry · 1988 · 245 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Structure of human β-glucuronidase reveals candidate lysosomal targeting and active-site motifs

Sanjeev Jain, William B. Drendel, Zhiwei Chen et al. · Nature Structural & Molecular Biology · 1996 · 218 citations

Life Sciences, Biochemistry, Molecular Biology +14