Daptomycin biosynthesis in Streptomyces roseosporus: cloning and analysis of the gene cluster and revision of peptide stereochemistry

Vivian Miao, Marie-Françoise Coëffet-LeGal, Paul Brian, +10

Microbiology

EngineeringProtein SynthesisBiosynthesisStreptomyces RoseosporusNatural Product Biosynthesis +14

Genetic Engineering in Streptomyces roseosporus to Produce Hybrid Lipopeptide Antibiotics

Vivian Miao, Marie-François Coëffet-Le Gal, Kien T. Nguyen, +11

Chemistry & Biology

BiosynthesisEngineeringAntimicrobial Resistance GeneBiotechnologyGenetic Engineering +7

Heterologous production of daptomycin in Streptomyces lividans

Julia Penn, Xiang Li, Andrew Whiting, +8

Journal of Industrial Microbiology & Biotechnology

Glyantrypine, a novel anthranilic acid-containing metabolite of Aspergillus clavatus

Julia Penn, Peter G. Mantle, John N. Bilton, +1

Journal of the Chemical Society Perkin Transactions 1

Aspergillus ClavatusBiosynthesisAntifungal AgentBiochemistryMedicine +7

Biosynthetic intermediates of indole-diterpenoid mycotoxins from selected transformations at C-10 of paxilline

Julia Penn, Peter G. Mantle

Phytochemistry

BiosynthesisEngineeringBiochemistryMycotoxin FormationNatural Product Biosynthesis +4

Rapid identification of microbial VOCs from tobacco molds using closed-loop stripping and gas chromatography/time-of-flight mass spectrometry

Naren K. Meruva, Julia Penn, Don Farthing

Journal of Industrial Microbiology & Biotechnology

Pennigritrem, a naturally-occurring penitrem A analogue with novel cyclisation in the diterpenoid moiety

Julia Penn, Jeremy Biddle, Peter G. Mantle, +2

Journal of the Chemical Society Perkin Transactions 1

Combinatorial ChemistryBioorganic ChemistryNmr SpectroscopySecondary MetaboliteOrganic Chemistry +15

Novel β-Methoxyacrylates of the 9-Methoxystrobilurin and Oudemansin Classes Produced by the Basidiomycete <i>Favolaschia pustulosa</i>

Keith A. Wood, DAVID A. KAU, Stephen K. Wrigley, +7

Journal of Natural Products

Janthitrems B and C, two principal indole-diterpenoids produced by Penicillium janthinellum

Julia Penn, Richard J. Swift, Lucy J. Wigley, +3

Phytochemistry

BiosynthesisPenicillium JanthinellumJanthitrems BPhytochemistryPharmacology +2

Anacine, a New Benzodiazepine Metabolite of Penicillium aurantiogriseum Produced with Other Alkaloids in Submerged Fermentation

Jane M. Boyes-Korkis, Karen Gurney, Julia Penn, +3

Journal of Natural Products

Therapeutic Drug MonitoringMedicinal ChemistryBiochemistryMedicineNatural Sciences +11