Therapeutic agents with dramatic antiretroviral activity and little toxicity at effective doses: aromatic polycyclic diones hypericin and pseudohypericin.

Daniel Meruelo, G. Lavie, David Lavie

Proceedings of the National Academy of Sciences

ImmunologyAntimicrobial ChemotherapyAntiviral DrugHypericum FamilyTherapeutic Agents +17

Degradation of serum amyloid A protein by surface-associated enzymes of human blood monocytes.

G. Lavie, Dorothea Zucker‐Franklin, E. C. Franklin

The Journal of Experimental Medicine

Alzheimer's DiseaseHuman Blood MonocytesBiochemistryOuter MembraneProtein Folding +11

Studies of the mechanisms of action of the antiretroviral agents hypericin and pseudohypericin.

G. Lavie, Fred Valentine, Brandi Levin, +5

Proceedings of the National Academy of Sciences

Electron MicroscopyNeurovirologyMedicinePathogenesisImmunology +13

Elastase-type proteases on the surface of human blood monocytes: possible role in amyloid formation.

G. Lavie, Dorothea Zucker‐Franklin, E. C. Franklin

The Journal of Immunology

Elastase-type ProteasesProtein FunctionHuman Blood MonocytesProtein ExpressionBiochemistry +13

Monoclonal anti-tuberculosis antibodies react with DNA, and monoclonal anti-DNA autoantibodies react with Mycobacterium tuberculosis.

Yehuda Shoenfeld, Yaffa Vilner, Anthony Coates, +4

PubMed

Humoral ResponseImmunologyImmunotherapyMycobacterium TuberculosisAutoantibodies +16

Hypericin as an inactivator of infectious viruses in blood components

G. Lavie, Y. MAZUR, David Lavie, +5

Transfusion

A photodynamic pathway to apoptosis and necrosis induced by dimethyl tetrahydroxyhelianthrone and hypericin in leukaemic cells: possible relevance to photodynamic therapy

G. Lavie, Chaim Kaplinsky, Amos Toren, +4

British Journal of Cancer

The detection of a common idiotype of anti-DNA antibodies in the sera of patients with monoclonal gammopathies

Yehuda Shoenfeld, O. Ben-Yehuda, Y. Napartstek, +9

Journal of Clinical Immunology

Anti-dna AntibodiesAutoimmune DiseaseMedicineImmunologyDiagnosis +5

The mechanism of human NK cell-mediated cytotoxicity. Mode of action of surface-associated proteases in the early stages of the lytic reaction.

G. Lavie, Z Leib, C Servadio

The Journal of Immunology

ImmunotoxicologyImmunologyPathologyCell DeathAntigen Processing +19

ANTI-cancer Activities of Hypericin in the Dark¶

Michael Blank, M. Mandel, Yona Keisari, +1

Photochemistry and Photobiology

Potent Photodynamic PropertiesPhotochemistryBiochemistryPhotodynamic TherapyMedicine +13