Reverse engineering of the giant muscle protein titin

Hongbin Li, Wolfgang A. Linke, Andrés F. Oberhauser, +5

Nature

Protein ChemistryProtein AssemblyProtein FoldingNatural SciencesMolecular Biology +5

Membrane bending occurs at all stages of clathrin-coat assembly and defines endocytic dynamics

Brandon L. Scott, Kem A. Sochacki, Shalini T. Low-Nam, +8

Nature Communications

Membrane StructureClathrin-coat AssemblySpherical VesiclesDefines Endocytic DynamicsMolecular Biology +15

Sterols lower energetic barriers of membrane bending and fission necessary for efficient clathrin-mediated endocytosis

Ruthellen H. Anderson, Kem A. Sochacki, Harika Vuppula, +7

Cell Reports

Lipid MovementEfficient Clathrin-mediated EndocytosisCellular PhysiologyMembrane TransportEndocytic Pathway +15

The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy

Shayne E. Quinn, Lu Huang, Jason G. Kerkvliet, +6

Nature Communications

Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells

Natesampillai Sekar, Jason G. Kerkvliet, Peter C. K. Leung, +1

American Journal of Physiology-Endocrinology and Metabolism

OocyteMolecular RegulationGeneticsCellular PhysiologyOvarian Cancer +18

Delivery of the CSF-1R to the lumen of macropinosomes promotes its destruction in macrophages

Jieqiong Lou, Shalini T. Low-Nam, Jason G. Kerkvliet, +1

Journal of Cell Science

InflammationMacrophage ColonySignal TransductionCell SignalingCell Trafficking +13

Both cytopathic and non-cytopathic bovine viral diarrhea virus (BVDV) induced autophagy at a similar rate

Mrigendra Rajput, Karim Abdelsalam, Mahmoud Darweesh, +4

Veterinary Immunology and Immunopathology

Viral PersistenceSimilar RatePathogenesisAutophagyImmunology +6

Antiviral Effects of a Transgenic RNA-Dependent RNA Polymerase

Jason G. Kerkvliet, Louisa Papke, Moses Rodriguez

Journal of Virology

Antiviral EffectsViral ReplicationPathogenesisImmunologyViral Pathogenesis +10

Transgenic Expression of the 3D Polymerase Inhibits Theiler's Virus Infection and Demyelination

Jason G. Kerkvliet, Laurie Zoecklein, Louisa Papke, +4

Journal of Virology

Viral ReplicationImmunologyViral Pathogenesis.3D MiceVirus Gene +15

Allelic variation in the Tyk2 and EGF genes as potential genetic determinants of CNS repair

Allan J. Bieber, Kanitta Suwansrinon, Jason G. Kerkvliet, +3

Proceedings of the National Academy of Sciences