Substrates and Regulation Mechanisms for the Human Mitochondrial Sirtuins Sirt3 and Sirt5

Christine Schlicker, M. Gertz, Panagiotis Papatheodorou, +3

Journal of Molecular Biology

Reductive StressMitophagyMitochondrial FunctionNatural SciencesGenetics +9

A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol

M. Gertz, Giang Thi Tuyet Nguyen, Frank Fischer, +8

PLoS ONE

Structure and Inhibition of the CO2-Sensing Carbonic Anhydrase Can2 from the Pathogenic Fungus Cryptococcus neoformans

Christine Schlicker, Rebecca A. Hall, Daniela Vullo, +5

Journal of Molecular Biology

Biological Carbon FixationBiochemistryBioenergeticsMicrobial PhysiologyFungal Physiology +2

Characterization of F107 fimbriae of Escherichia coli 107/86, which causes edema disease in pigs, and nucleotide sequence of the F107 major fimbrial subunit gene, fedA

Hein Imberechts, Henri De Greve, Christine Schlicker, +7

Infection and Immunity

Microbial PathogensPathogen DetectionBacteriologyPathologyEscherichia Coli +14

Engineering and application of a biosensor with focused ligand specificity

Dennis Della Corte, Hugo L. van Beek, Falk Syberg, +12

Nature Communications

Crystal structure of mammalian selenocysteine-dependent iodothyronine deiodinase suggests a peroxiredoxin-like catalytic mechanism

Ulrich Schweizer, Christine Schlicker, Doreen Braun, +2

Proceedings of the National Academy of Sciences

Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with aliphatic and aromatic carboxylates

Alessio Innocenti, Rebecca A. Hall, Christine Schlicker, +2

Bioorganic & Medicinal Chemistry

β-Class EnzymesAntifungal AgentBiochemistryFungal Cell BiologyCryptococcus Neoformans +2

Structural Analysis of the PP2C Phosphatase tPphA from Thermosynechococcus elongatus: A Flexible Flap Subdomain Controls Access to the Catalytic Site

Christine Schlicker, Oleksandra Fokina, Nicole Kloft, +4

Journal of Molecular Biology

Pp2c Phosphatase TpphaBiochemistryCellular EnzymologyNatural SciencesEnzyme Catalysis +6

Structure-based development of novel sirtuin inhibitors

Christine Schlicker, Gina Boanca, Mahadevan Lakshminarasimhan, +1

Aging

Molecular DockingMedicinal ChemistryHuman SirtuinsProtein FunctionBiochemistry +13

Isolation and nucleotide sequence of the F17-A gene encoding the structural protein of the F17 fimbriae in bovine enterotoxigenic Escherichia coli

P. Lintermans, P. Pohl, Francine Deboeck, +6

Infection and Immunity

BacteriologyMolecular BiologyMolecular GeneticsProtein SynthesisProtein Expression +17