T R Skopek

DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea.

Katherine K. Richardson, Frank C. Richardson, Renae M. Crosby et al. · Proceedings of the National Academy of Sciences · 1987 · 229 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Mutagenicity of butadiene and its epoxide metabolites: I. Mutagenic potential of 1,2-epoxybutene, 1,2,3,4-diepoxybutane and 3,4-epoxy-1,2-butanediol in cultured human lymphoblasts

J.E. Cochrane, T R Skopek · Carcinogenesis · 1994 · 209 citations

Pharmacy, Toxicology, Carcinogenesis +15

Quantitative forward mutation assay in Salmonella typhimurium using 8-azaguanine resistance as a genetic marker.

T R Skopek, Howard L. Liber, John J. Krolewski et al. · Proceedings of the National Academy of Sciences · 1978 · 158 citations · Full text

Life Sciences, Genetics, Microbiology +15

Mutagenicity of butadiene and its epoxide metabolites: II. Mutational spectra of butadiene, 1,2-epoxybutene and diepoxybutane at the <i>hprt</i> locus in splenic T cells from exposed B6C3F1 mice

J.E. Cochrane, T R Skopek · Carcinogenesis · 1994 · 152 citations

Pharmacy, Genetics, Toxicology +17

Efficient repair of O6-ethylguanine, but not O4-ethylthymine or O2-ethylthymine, is dependent upon O6-alkylguanine-DNA alkyltransferase and nucleotide excision repair activities in human cells.

S. Maynard Bronstein, T R Skopek, James A. Swenberg · PubMed · 1992 · 134 citations

Life Sciences, Molecular Biology, Oncology +17