Varsha Iyer

The allosteric inhibitor ABL001 enables dual targeting of BCR–ABL1

Andrew A. Wylie, Joseph Schoepfer, Wolfgang Jahnke et al. · Nature · 2017 · 596 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1

Joseph Schoepfer, Wolfgang Jahnke, Giuliano Berellini et al. · Journal of Medicinal Chemistry · 2018 · 447 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Use of Pharmacokinetic-Pharmacodynamic Analyses To Optimize Therapy with the Systemic Antifungal Micafungin for Invasive Candidiasis or Candidemia

David R. Andes, Paul G. Ambrose, Jeffrey Hammel et al. · Antimicrobial Agents and Chemotherapy · 2011 · 119 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

A phase 1 dose escalation study of the pyruvate kinase activator mitapivat (AG-348) in sickle cell disease

Julia Xu, Anna Conrey, Ingrid Frey et al. · Blood · 2022 · 72 citations · Full text

Life Sciences, Pharmacotherapy, Cell Signaling +8

Differential phosphorylation and dephosphorylation of <i>β</i>₂‐adrenoceptor sites Ser262 and Ser355,356

Varsha Iyer, Tuan M. Tran, Estrella A. Foster et al. · British Journal of Pharmacology · 2005 · 50 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17