Thrombin Production, Inactivation and Expression during Open Heart Surgery Measured by Assays for Activation Fragments Including a New ELISA for Prothrombin Fragment F1+2

Michael D. Boisclair, David A. Lane, Helen Philippou, +2

Thrombosis and Haemostasis

Synthesis and Biological Evaluation of 1-Aryl-4,5-dihydro-1<i>H</i>-pyrazolo[3,4-<i>d</i>]pyrimidin-4-one Inhibitors of Cyclin-Dependent Kinases

Jay A. Markwalder, Marc R. Arnone, Pamela A. Benfield, +18

Journal of Medicinal Chemistry

High-throughput Screening StrategyDrug TargetMolecular BiologyChemical BiologyPharmaceutical Chemistry +16

Quinazolines as cyclin dependent kinase inhibitors

Thais M. Sielecki, Tricia L. Johnson, Jie Liu, +12

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryMedicineMechanism Of ActionPharmacotherapyPharmacology +4

Indenopyrazoles as Novel Cyclin Dependent Kinase (CDK) Inhibitors

David A. Nugiel, Ana-Marie Etzkorn, Anup Vidwans, +7

Journal of Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryMolecular SciencesDrug TargetBiochemistry +13

Structure–activity relationship studies of flavopiridol analogues

Krishna K. Murthi, Marja Dubay, Christopher McClure, +5

Bioorganic & Medicinal Chemistry Letters

BiochemistryFlavopiridol AnaloguesMedicinePhytochemicalPhytochemistry +2

Unusual redox behaviour of cytochrome b-561 from bovine chromaffin granule membranes

David K. Apps, Michael D. Boisclair, Fiona S. Gavine, +1

Biochimica et Biophysica Acta (BBA) - Bioenergetics

BiochemistryNatural SciencesMembrane TransportBioanalysisUnusual Redox Behaviour +7

Identification of selective inhibitors of cyclin dependent kinase 4

David J. Carini, Robert F. Kaltenbach, Jie Liu, +16

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDrug TargetBiochemistryMedicineNatural Sciences +6

Synthesis and phosphatase inhibitory activity of analogs of sulfircin

Regina E.J. Cebula, Jill L. Blanchard, Michael D. Boisclair, +2

Bioorganic & Medicinal Chemistry Letters

BiochemistryPhosphatase Inhibitory ActivityNatural SciencesMechanism Of ActionChemical Biology +2

Dysidiolide and related γ-hydroxy butenolide compounds as inhibitors of the protein tyrosine phosphatase, CDC25

Jill L. Blanchard, David Epstein, Michael D. Boisclair, +2

Bioorganic & Medicinal Chemistry Letters

Protein Tyrosine PhosphataseBiochemistryMedicineNatural SciencesMechanism Of Action +6

Development of a Ubiquitin Transfer Assay for High Throughput Screening by Fluorescence Resonance Energy Transfer

Michael D. Boisclair, Christopher McClure, Serene Josiah, +4

SLAS DISCOVERY