Phosphorylation of large tumour antigen by cdc2 stimulates SV40 DNA replication

Duncan McVey, Leonardo Brizuela, Ian Mohr, +3

Nature

Large Tumour AntigenGenome InstabilitySignal TransductionCell RegulationNatural Sciences +7

Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor.

Keisuke Mori, Peter Gehlbach, Akira Ando, +3

PubMed

Induction of antitumor immunity by direct intratumoral injection of a recombinant adenovirus vector expressing interleukin-12

Andrea Gambotto, Thomas Tüting, Duncan McVey, +4

Cancer Gene Therapy

Cancer ImmunosurveillanceRecombinant Adenovirus VectorImmunologyTumor ImmunityTherapeutic Vaccine +7

cdc2 phosphorylation of threonine 124 activates the origin-unwinding functions of simian virus 40 T antigen

Duncan McVey, Satyajit Ray, Y Gluzman, +4

Journal of Virology

Viral ReplicationGeneticsImmunologyMolecular BiologyAntigen Processing +15

Expression of gp19K increases the persistence of transgene expression from an adenovirus vector in the mouse lung and liver

Joseph T. Bruder, Duncan McVey, Imre Kovesdi

Journal of Virology

Viral ReplicationTransgene ExpressionImmunologyPathologyImmunotherapy +14

Intraocular adenoviral vector-mediated gene transfer in proliferative retinopathies.

Keisuke Mori, Peter Gehlbach, Akira Ando, +5

PubMed

Mechanisms of simian virus 40 T-antigen activation by phosphorylation of threonine 124

Duncan McVey, Birgit Woelker, P Tegtmeyer

Journal of Virology

Viral ReplicationSv40 OriginT-antigen ActivationImmunologyMolecular Biology +17

Production of simian virus 40 large tumor antigen in bacteria: altered DNA-binding specificity and dna-replication activity of underphosphorylated large tumor antigen.

Ian Mohr, Y Gluzman, M. P. Fairman, +4

Proceedings of the National Academy of Sciences

Viral ReplicationImmunologyMolecular BiologyAntigen ProcessingT Antigen +15

Functional characterization of temperature-sensitive mutants of simian virus 40 large T antigen

Satyajit Ray, Mary E. Anderson, G Loeber, +2

Journal of Virology

Atpase ActivityVirus StructureViral ReplicationLarge T AntigenAmino Acid 186 +12

Properties of the DNA-binding domain of the simian virus 40 large T antigen.

Duncan McVey, Mike Strauss, Y Gluzman

Molecular and Cellular Biology

Viral ReplicationLarge T AntigenAmino AcidsImmunologyMolecular Biology +14