Joseph T. Bruder

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

Xianfeng Zhang, Jeffrey Settleman, John Kyriakis et al. · Nature · 1993 · 874 citations

Protein Function, Molecular Regulation, Natural Sciences +8

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase.

Joseph T. Bruder, Gisela Heidecker, Ulf R. Rapp · Genes & Development · 1992 · 451 citations · Full text

Molecular Regulation, Immunology, Cysteine Finger Motif +18

UV-induced activation of AP-1 involves obligatory extranuclear steps including Raf-1 kinase.

Adriana Radler‐Pohl, Christoph Sachsenmaier, Stephan Gebel et al. · The EMBO Journal · 1993 · 257 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +11

Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires Raf and is necessary for transformation.

Jakob Troppmair, Joseph T. Bruder, Hugo Roberto Muñoz et al. · Journal of Biological Chemistry · 1994 · 240 citations · Full text

Signal Transduction, Signaling Pathway, Biochemistry +12

Adenovirus infection stimulates the Raf/MAPK signaling pathway and induces interleukin-8 expression

Joseph T. Bruder, Imre Kovesdi · Journal of Virology · 1997 · 229 citations · Full text

Inflammatory Lung Disease, Immunology, Viral Pathogenesis +18