An-Hsun Chou

Polyglutamine-expanded ataxin-3 causes cerebellar dysfunction of SCA3 transgenic mice by inducing transcriptional dysregulation

An-Hsun Chou, Tu‐Hsueh Yeh, Pin Ouyang et al. · Neurobiology of Disease · 2008 · 179 citations · Full text

Knockout Mouse, Neurodegenerative Diseases, Sca3 Transgenic Mice +8

PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons

Hung‐Li Wang, An-Hsun Chou, Ai-Shun Wu et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2011 · 120 citations · Full text

Mitophagy, Mitochondrial Function, Dopaminergic Neurons +6

Polyglutamine-expanded ataxin-3 activates mitochondrial apoptotic pathway by upregulating Bax and downregulating Bcl-xL

An-Hsun Chou, Tu‐Hsueh Yeh, Yu-Li Kuo et al. · Neurobiology of Disease · 2005 · 95 citations · Full text

Signal Transduction, Mitochondrial Function, Apoptosis +6

HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3

An-Hsun Chou, Si-Ying Chen, Tu‐Hsueh Yeh et al. · Neurobiology of Disease · 2010 · 95 citations · Full text

Transcriptional Downregulation, Knockout Mouse, Transcriptional Regulation +9

PINK1 mutants associated with recessive Parkinson’s disease are defective in inhibiting mitochondrial release of cytochrome c

Hung‐Li Wang, An-Hsun Chou, Tu‐Hsueh Yeh et al. · Neurobiology of Disease · 2007 · 86 citations · Full text

Mitochondrial Release, Neurodegenerative Diseases, Biochemistry +8