John Mcelroy

4-(1,3-Dimethoxyprop-2-ylamino)-2,7-dimethyl-8-(2,4-dichlorophenyl)pyrazolo[1,5-<i>a</i>]-1,3,5-triazine:  A Potent, Orally Bioavailable CRF₁ Receptor Antagonist

Liqi He, Paul J. Gilligan, Robert Zaczek et al. · Journal of Medicinal Chemistry · 2000 · 113 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

The discovery of 4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-a]-pyrimidine: A corticotropin-releasing factor (hCRF1) antagonist

Paul J. Gilligan, Caryn Baldauf, Anthony J. Cocuzza et al. · Bioorganic & Medicinal Chemistry · 2000 · 83 citations

Medicine, Medicinal Chemistry, Pharmacology +4

Receptor Occupancy of Nonpeptide Corticotropin-Releasing Factor 1 Antagonist DMP696: Correlation with Drug Exposure and Anxiolytic Efficacy

Yu-Wen Li, Geraldine Hill, Harvey Wong et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 60 citations

Medicine, Neuroscience, Pharmacology +14

The CRF 1 receptor antagonist DMP696 produces anxiolytic effects and inhibits the stress-induced hypothalamic-pituitary-adrenal axis activation without sedation or ataxia in rats

John Mcelroy, Kim Zeller, Keith Jones et al. · Psychopharmacology · 2002 · 42 citations

Medicine, Neuroscience, Pharmacology +17

8-(4-Methoxyphenyl)pyrazolo[1,5-<i>a</i>]-1,3,5-triazines: Selective and Centrally Active Corticotropin-Releasing Factor Receptor-1 (CRF₁) Antagonists

Paul J. Gilligan, Liqi He, Todd Clarke et al. · Journal of Medicinal Chemistry · 2009 · 34 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15