Stephen D. Penrose

Design, Synthesis, and Biological Evaluation of Potent and Selective Class IIa Histone Deacetylase (HDAC) Inhibitors as a Potential Therapy for Huntington’s Disease

Roland W. Bürli, Christopher A. Luckhurst, Omar Aziz et al. · Journal of Medicinal Chemistry · 2013 · 147 citations · Full text

Aldo-keto Reductase, Molecular Biology, Chemical Biology +19

Rhodium-Catalyzed Conjugate Addition−Enantioselective Protonation:  The Synthesis of α,α‘-Dibenzyl Esters

Christopher G. Frost, Stephen D. Penrose, Kim Lambshead et al. · Organic Letters · 2007 · 57 citations

Rhodium catalysed conjugate addition of a chiral alkenyltrifluoroborate salt: the enantioselective synthesis of hermitamides A and B

Christopher G. Frost, Stephen D. Penrose, Robert J. Gleave · Organic & Biomolecular Chemistry · 2008 · 24 citations

Asymmetric Catalysis, Chemical Engineering, Enantioselective Synthesis +11

Optimization of Potent and Selective Ataxia Telangiectasia-Mutated Inhibitors Suitable for a Proof-of-Concept Study in Huntington’s Disease Models

Leticia Toledo‐Sherman, Perla Breccia, Roger Cachope et al. · Journal of Medicinal Chemistry · 2019 · 24 citations · Full text

Genetics, Molecular Biology, Pharmacotherapy +17

Exploring Rhodium-Catalysed Conjugate Addition of Chiral Alkenylboronates Using Chiral Olefin Ligands

Christopher G. Frost, Hannah J. Edwards, Stephen D. Penrose et al. · Synthesis · 2010 · 12 citations

Chemical Engineering, Cross-coupling Reaction, Engineering +13