Andrew S. Rosenthal

A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses

Liang Qin, Thomas S. Dexheimer, Ping Zhang et al. · Nature Chemical Biology · 2014 · 265 citations · Full text

Genome Instability, Genomic Mechanism, Molecular Biology +2

A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

Giang Huong Nguyen, Thomas S. Dexheimer, Andrew S. Rosenthal et al. · Chemistry & Biology · 2013 · 162 citations · Full text

Chromatin, Chromatin Structure, Chromatin Remodeling +8

Accumulation of artemisinin trioxane derivatives within neutral lipids of Plasmodium falciparum malaria parasites is endoperoxide-dependent

Carmony L. Hartwig, Andrew S. Rosenthal, John G. D’Angelo et al. · Biochemical Pharmacology · 2008 · 140 citations · Full text

Bioorganic Chemistry, Biochemistry, Antiparasitic Agent +7

Malaria-Infected Mice Are Cured by a Single Oral Dose of New Dimeric Trioxane Sulfones Which Are Also Selectively and Powerfully Cytotoxic to Cancer Cells

Andrew S. Rosenthal, Xiaochun Chen, Jun O. Liu et al. · Journal of Medicinal Chemistry · 2009 · 76 citations · Full text

Powerfully Cytotoxic, Chemoprevention Strategy, Antiparasitic Agent +17

Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk)

Andrew S. Rosenthal, Cordelle Tanega, Min Shen et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 71 citations · Full text

Signal Transduction, Specific Isoforms, Signaling Pathway +11