James L. Flowers

Differential Activation of ERK and Rac Mediates the Proliferative and Anti-proliferative Effects of Hyaluronan and CD44

Devashish Kothapalli, James L. Flowers, Tina Xu et al. · Journal of Biological Chemistry · 2008 · 90 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Early life adversity promotes resilience to opioid addiction-related phenotypes in male rats and sex-specific transcriptional changes

Evelyn Ordoñes Sanchez, Charlotte C. Bavley, André U. Deutschmann et al. · Proceedings of the National Academy of Sciences · 2021 · 70 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Camptothecin analogs with enhanced activity against human breast cancer cells. II. Impact of the tumor pH gradient

David J. Adams, M Wahl, James L. Flowers et al. · Cancer Chemotherapy and Pharmacology · 2005 · 63 citations

Medicine, Oncology, Pharmacology +12

Camptothecin analogues with enhanced antitumor activity at acidic pH

David J. Adams, Mark W. Dewhirst, James L. Flowers et al. · Cancer Chemotherapy and Pharmacology · 2000 · 59 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Evidence for a role of chloroethylaziridine in the cytotoxicity of cyclophosphamide

James L. Flowers, Susan M. Ludeman, Michael P. Gamcsik et al. · Cancer Chemotherapy and Pharmacology · 2000 · 42 citations

Pharmacy, Pharmacology, Toxicology +5