Hong Chang

A Phase I Study of the Pan Bcl-2 Family Inhibitor Obatoclax Mesylate in Patients with Advanced Hematologic Malignancies

Aaron D. Schimmer, Susan O’Brien, Hagop M. Kantarjian et al. · Clinical Cancer Research · 2008 · 186 citations · Full text

Medicine, Hematology, Pharmacology +16

Antiangiogenic and Antitumor Efficacy of EphA2 Receptor Antagonist

Paweł Dobrzański, Kathryn Hunter, Susan Jones‐Bolin et al. · Cancer Research · 2004 · 160 citations

Medicine, Oncology, Pharmacology +13

CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models.

Bruce Ruggeri, Diane E. Gingrich, Thelma S. Angeles et al. · PubMed · 2003 · 124 citations

Medicine, Oncology, Pharmacology +15

Structure-guided identification of novel VEGFR-2 kinase inhibitors via solution phase parallel synthesis

Rabindranath Tripathy, Alyssa Reiboldt, Patricia A. Messina et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 105 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

The neurotrophin-trk receptor axes are critical for the growth and progression of human prostatic carcinoma and pancreatic ductal adenocarcinoma xenografts in nude mice.

Sheila Miknyoczki, Weihua Wan, Hong Chang et al. · PubMed · 2002 · 91 citations

Medicine, Cancer Biology, Oncology +14