Jeffim N. Kuznetsov

Single-cell analysis reveals new evolutionary complexity in uveal melanoma

Michael Durante, Daniel A. Rodriguez, Stefan Kurtenbach et al. · Nature Communications · 2020 · 481 citations · Full text

Medicine, Immunology, Oncology +17

Epigenetic reprogramming and aberrant expression of PRAME are associated with increased metastatic risk in Class 1 and Class 2 uveal melanomas

Matthew G. Field, Michael Durante, Christina L. Decatur et al. · Oncotarget · 2016 · 124 citations · Full text

Medicine, Genetics, Oncology +17

Metformin Induces Apoptosis through AMPK-Dependent Inhibition of UPR Signaling in ALL Lymphoblasts

Gilles M. Leclerc, Guy J. Leclerc, Jeffim N. Kuznetsov et al. · PLoS ONE · 2013 · 107 citations · Full text

Life Sciences, Oncology, Pharmacology +17

AMPK and Akt Determine Apoptotic Cell Death following Perturbations of One-Carbon Metabolism by Regulating ER Stress in Acute Lymphoblastic Leukemia

Jeffim N. Kuznetsov, Guy J. Leclerc, Gilles M. Leclerc et al. · Molecular Cancer Therapeutics · 2011 · 90 citations · Full text

Life Sciences, Oncology, Pharmacology +17

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers

Jeffim N. Kuznetsov, Tristan Agüero, Dawn A. Owens et al. · Science Advances · 2019 · 86 citations · Full text

Medicine, Cancer Biology, Molecular Biology +14