Hitoshi Sakaguchi

Assessing skin sensitization hazard in mice and men using non-animal test methods

Daniel Urbisch, Annette Mehling, Katharina Guth et al. · Regulatory Toxicology and Pharmacology · 2014 · 394 citations · Full text

Life Sciences, Dermatology, Toxicology +17

Systematic evaluation of non-animal test methods for skin sensitisation safety assessment

Kerstin Reisinger, Sebastian Hoffmann, Nathalie Alépée et al. · Toxicology in Vitro · 2014 · 132 citations · Full text

Pharmacy, Dermatology, Toxicology +17

A Comparative Evaluation of <i>In Vitro</i> Skin Sensitisation Tests: The Human Cell-line Activation Test (h-CLAT) <i>versus</i> the Local Lymph Node Assay (LLNA)

Takao Ashikaga, Hitoshi Sakaguchi, Sakiko Sono et al. · Alternatives to Laboratory Animals · 2010 · 117 citations

Life Sciences, Dermatology, Immunology +14

Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency

Yuko Nukada, Takao Ashikaga, Masaaki Miyazawa et al. · Toxicology in Vitro · 2012 · 116 citations

Pharmacy, Dermatology, Toxicology +13

The relationship between CD86/CD54 expression and THP-1 cell viability in an in vitro skin sensitization test – human cell line activation test (h-CLAT)

Hitoshi Sakaguchi, Takao Ashikaga, Masaaki Miyazawa et al. · Cell Biology and Toxicology · 2008 · 107 citations

Life Sciences, Cell Biology, Immunology +14