Shawn Kothari

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response

Alexander C. Huang, Michael A. Postow, Robert J. Orlowski et al. · Nature · 2017 · 1.7K citations · Full text

Life Sciences, Immunology, Oncology +16

Pretreatment neutrophil-to-lymphocyte ratio as a marker of outcomes in nivolumab-treated patients with advanced non-small-cell lung cancer

Stephen Bagley, Shawn Kothari, Charu Aggarwal et al. · Lung Cancer · 2017 · 529 citations

Medicine, Immunology, Oncology +16

Repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab show no efficacy in glioblastoma: a phase 1 trial

Stephen Bagley, Zev A. Binder, Lamia Lamrani et al. · Nature Cancer · 2024 · 169 citations · Full text

Medicine, Oncology, Pharmacology +17

Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells

Kevin Wang, Paulina Coutifaris, David Brocks et al. · Cancer Cell · 2024 · 96 citations · Full text

Life Sciences, Immunology, Oncology +16

Dose escalation prophylactic donor lymphocyte infusion after T-cell depleted matched related donor allogeneic hematopoietic cell transplantation is feasible and results in higher donor chimerism, faster immune re-constitution, and prolonged progression-free survival

Shawn Kothari, Andrew Artz, Sang Mee Lee et al. · Bone Marrow Transplantation · 2020 · 17 citations

Medicine, Hematology, Immunology +15