Nathan Osman

Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure

Thibault Mésplède, Peter K. Quashie, Nathan Osman et al. · Retrovirology · 2013 · 132 citations · Full text

Life Sciences, Infectious Diseases, Pharmacotherapy +17

The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness

Melissa Wares, Thibault Mésplède, Peter K. Quashie et al. · Retrovirology · 2014 · 80 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Differential Effects of the G118R, H51Y, and E138K Resistance Substitutions in Different Subtypes of HIV Integrase

Peter K. Quashie, M Oliviera, Tamar Veres et al. · Journal of Virology · 2015 · 76 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Evaluation of Sofosbuvir (β-D-2′-deoxy-2′-α-fluoro-2′-β-C-methyluridine) as an inhibitor of Dengue virus replication #

Hongtao Xu, Susan P. Colby-Germinario, Said Hassounah et al. · Scientific Reports · 2017 · 73 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase

Peter K. Quashie, Thibault Mésplède, Ying-Shan Han et al. · Antimicrobial Agents and Chemotherapy · 2013 · 67 citations · Full text

Life Sciences, Genetics, Molecular Biology +17